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Products:Neuroscience >> Neurology process >> Neurodegenerative disease >> Alzheimer's disease >> Other
Overview
Product name
Diazepam Binding Inhibitor protein (Tagged)
See all Diazepam Binding Inhibitor products (2) ...
Protein description
Recombinant full length human Diazepam Binding Inhibitor with proprietary tag; amino acids 1-87, 38kDa. Swiss ID = P07108
Expression host
E. coli
Properties
Purity
Purified via GST Tag
Purification notes
Purified
Form
Lyophilised:
Reconstitute in 20mM HEPES, pH 7.0
Storage instructions
Aliquot and store at -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: None
Constituents: 10% Glycerol, 20mM HEPES, pH 7.0
Concentration
Concentration information loading...
Additional notes
ab84342 is supplied with a vial of storage buffer (20mM HEPES, pH7.0/10%
Glycerol).
Research areas
Neuroscience >> Neuropharmacology >> Molecular Neuropharmacology
Neuroscience >> Neurology process >> Neurodegenerative disease >> Alzheimer's disease >> Other
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SDS-PAGE - Diazepam Binding Inhibitor protein (Tagged) (ab84342)
(enlarge)
Applications
Show applications key
Our Abpromise guarantee covers the use of ab84342 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
SDS-PAGE: Use at an assay dependent dilution.
Protein info
Function
Binds medium- and long-chain acyl-CoA esters with very high affinity and may function as an intracellular carrier of acyl-CoA esters. It is also able to displace diazepam from the benzodiazepine (BZD) recognition site located on the GABA type A receptor. It is therefore possible that this protein also acts as a neuropeptide to modulate the action of the GABA receptor.
Tissue specificity
Isoform 1 is ubiquitous, with a moderate expression level. Isoform 2 is ubiquitous with high level in liver and adipose tissue. Isoform 3 is ubiquitous with strong expression in adipose tissue and heart.
Sequence similarities
Belongs to the ACBP family.
Contains 1 ACB (acyl-CoA-binding) domain.
Target information above from: UniProt accessionP07108
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Diazepam Binding Inhibitor protein (Tagged) images:
SDS-PAGE - Diazepam Binding Inhibitor protein (Tagged) (ab84342)
SDS-PAGE showing ab84342 at approximately 38kDa (1µg).
References for Diazepam Binding Inhibitor protein (Tagged) (ab84342)
ab84342 has not yet been referenced specifically in any publications.
Publishing research using ab84342? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"