Overview

  • Product nameAnti-Dishevelled 3 antibodySee all Dishevelled 3 primary antibodies ...
  • Description
    Rabbit polyclonal to Dishevelled 3
  • Specificityab22617 recognises dishevelled 1. It doesn't recognise dishevelled 2 or dishevelled 3. By BLAST search of the immunogen aminoacids sequence, ab22617 may recognise human Hypothetical protein DKFZp586M1622 and human Protein kinase C-binding protein RACK8.
  • Tested applicationsWBmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    Synthetic peptide:

    C+GSDRRKEKDPKAGDS

    conjugated to KLH by a MBS linker, corresponding to amino acids 582/596 of Human Dishevelled 3.

Properties

Applications

Our Abpromise guarantee covers the use of ab22617 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
  • Application notesWB: 1/1000. Detects a band of approximately 90 kDa (predicted molecular weight: 78 kDa).

    Note: there is a weak reactivity observed with dishevelled 1 and dishevelled 2 that is due to protein protein interaction, and is not abolished following peptide preadsorption.

    Note: dilute ab22617 to working strength in 50mM PBS (pH 7.4) containing 1.5% sodium chloride and 1% normal goat serum (if a goat anti rabbit IgG linker antibody is to be used).



    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionMay play a role in the signal transduction pathway mediated by multiple Wnt genes.
    • Sequence similaritiesBelongs to the DSH family.
      Contains 1 DEP domain.
      Contains 1 DIX domain.
      Contains 1 PDZ (DHR) domain.
    • Post-translational
      modifications
      Ubiquitinated. Deubiquitinated by CYLD, which acts on 'Lys-63'-linked ubiquitin chains.
    • Cellular localizationCytoplasm.
    • Information by UniProt
    • Database links
    • Alternative names
      • Dishevelled 3 (homologous to Drosophila dsh) antibody
      • Dishevelled 3 antibody
      • Dishevelled 3, dsh homolog (Drosophila) antibody
      • Dishevelled, dsh homolog 3 (Drosophila) antibody
      • Dishevelled-3 antibody
      • DSH homolog 3 antibody
      • DVL3 antibody
      • DVL3_HUMAN antibody
      • KIAA0208 antibody
      • KIAA0208 antibody
      • OTTHUMP00000210777 antibody
      • OTTHUMP00000210778 antibody
      • Segment polarity protein dishevelled homolog DVL 3 antibody
      • Segment polarity protein dishevelled homolog DVL 3 antibody
      • Segment polarity protein dishevelled homolog DVL-3 antibody
      see all

    References for Anti-Dishevelled 3 antibody (ab22617)

    ab22617 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab22617.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"