Anti-Dishevelled 3 antibody (ab22617)
- Product nameAnti-Dishevelled 3 antibodySee all Dishevelled 3 primary antibodies ...
- DescriptionRabbit polyclonal to Dishevelled 3
- Specificityab22617 recognises dishevelled 1. It doesn't recognise dishevelled 2 or dishevelled 3. By BLAST search of the immunogen aminoacids sequence, ab22617 may recognise human Hypothetical protein DKFZp586M1622 and human Protein kinase C-binding protein RACK8.
- Tested applicationsWB more details
- Species reactivityReacts with: Mouse, Human
Synthetic peptide: C+GSDRRKEKDPKAGDS conjugated to KLH by a MBS linker, corresponding to amino acids 582/596 of Human Dishevelled 3.
- Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
- Storage bufferPreservative: 10mM Sodium Azide
Constituents: PBS, pH 7.4
- Concentration information loading...
- Purification notesab22617 is rabbit antiserum partially purified by caprylic acid and ammonium sulphate precipitation.
- Clonality Polyclonal
- Research Areas
Our Abpromise guarantee covers the use of ab22617 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Note: there is a weak reactivity observed with dishevelled 1 and dishevelled 2 that is due to protein protein interaction, and is not abolished following peptide preadsorption.
Note: dilute ab22617 to working strength in 50mM PBS (pH 7.4) containing 1.5% sodium chloride and 1% normal goat serum (if a goat anti rabbit IgG linker antibody is to be used).
Not tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
- FunctionMay play a role in the signal transduction pathway mediated by multiple Wnt genes.
- Sequence similaritiesBelongs to the DSH family.
Contains 1 DEP domain.
Contains 1 DIX domain.
Contains 1 PDZ (DHR) domain.
modificationsUbiquitinated. Deubiquitinated by CYLD, which acts on 'Lys-63'-linked ubiquitin chains.
- Cellular localizationCytoplasm.
- Dishevelled 3 (homologous to Drosophila dsh) antibodyDishevelled 3 antibodyDishevelled 3, dsh homolog (Drosophila) antibody
- Dishevelled, dsh homolog 3 (Drosophila) antibodyDishevelled-3 antibodyDSH homolog 3 antibodyDVL3 antibodyDVL3_HUMAN antibodyKIAA0208 antibodyKIAA0208 antibodyOTTHUMP00000210777 antibodyOTTHUMP00000210778 antibodySegment polarity protein dishevelled homolog DVL 3 antibodySegment polarity protein dishevelled homolog DVL 3 antibodySegment polarity protein dishevelled homolog DVL-3 antibody
References for Anti-Dishevelled 3 antibody (ab22617)
ab22617 has not yet been referenced specifically in any publications.