Overview

  • Product nameAnti-Dishevelled 3 antibodySee all Dishevelled 3 primary antibodies ...
  • Description
    Rabbit polyclonal to Dishevelled 3
  • Tested applicationsWBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Synthetic peptide conjugated to KLH derived from within residues 50 - 150 of Human Dishevelled 3.

    (Peptide available as ab108471.)

  • Positive control
    • This antibody gave a positive signal in the following lysates: Ovary (Human) Tissue Lysate; Heart (Human) Tissue Lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab93850 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 mg/ml. Detects a band of approximately 78 kDa (predicted molecular weight: 78 kDa).Can be blocked with Dishevelled 3 peptide (ab108471).

Target

  • FunctionMay play a role in the signal transduction pathway mediated by multiple Wnt genes.
  • Sequence similaritiesBelongs to the DSH family.
    Contains 1 DEP domain.
    Contains 1 DIX domain.
    Contains 1 PDZ (DHR) domain.
  • Post-translational
    modifications
    Ubiquitinated. Deubiquitinated by CYLD, which acts on 'Lys-63'-linked ubiquitin chains.
  • Cellular localizationCytoplasm.
  • Information by UniProt
  • Database links
  • Alternative names
    • Dishevelled 3 (homologous to Drosophila dsh) antibody
    • Dishevelled 3 antibody
    • Dishevelled 3, dsh homolog (Drosophila) antibody
    • Dishevelled, dsh homolog 3 (Drosophila) antibody
    • Dishevelled-3 antibody
    • DSH homolog 3 antibody
    • DVL3 antibody
    • DVL3_HUMAN antibody
    • KIAA0208 antibody
    • OTTHUMP00000210777 antibody
    • OTTHUMP00000210778 antibody
    • Segment polarity protein dishevelled homolog DVL 3 antibody
    • Segment polarity protein dishevelled homolog DVL-3 antibody
    see all

Anti-Dishevelled 3 antibody images

  • All lanes : Anti-Dishevelled 3 antibody (ab93850) at 1 µg/ml

    Lane 1 : Ovary (Human) Tissue Lysate - adult normal tissue (ab30222)
    Lane 2 : Heart (Human) Tissue Lysate - adult normal tissue (ab29431)

    Lysates/proteins at 10 µg per lane.

    Secondary
    Goat polyclonal Secondary Antibody to Rabbit IgG - H&L (HRP), pre-adsorbed at 1/5000 dilution
    developed using the ECL technique

    Performed under reducing conditions.

    Predicted band size : 78 kDa
    Observed band size : 78 kDa
    Additional bands at : 50 kDa. We are unsure as to the identity of these extra bands.

    Exposure time : 3 minutes

References for Anti-Dishevelled 3 antibody (ab93850)

ab93850 has not yet been referenced specifically in any publications.

Product Wall

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