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Dynamin Inhibitors: Iminodyn™ Series Kit

Product code: ab120475 (formerly Asc-475)

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Overview

Product name

Dynamin Inhibitors: Iminodyn™ Series Kit

Product overview

IminodynTM chemical series collection


Convenient kit containing dynamin inhibitor Iminodyn-22™ (ab120461; 1 mg) and Iminodyn-17™ (ab120462; 1 mg) from the Iminodyn chemical series. Iminodyn-22™ (ab120461) targets dynamin at the GTPase Allosteric Site (GAS) domain. It potently inhibits both dynamin I and II in enzymatic assays and is a potent inhibitor of receptor-mediated endocytosis in cells. Iminodyn-17™ inhibits dynamin I and II in enzymatic assays, but does not affect dynamin mediated endocytosis in cells. It can therefore be used as a negative control for cell based assays.






















TargetDescription
GTPase Allosteric Site

Iminodyn-22™:


Potent, broad spectrum dynamin inhibitor

GTPase Allosteric Site

Iminodyn-17™:


Negative control for Iminodyn-22™

Notes

Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 6 months.

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one week. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Sold under exclusive licence from Children's Medical Research Institute and Newcastle Innovation Ltd. Iminodyn-22™ and Iminodyn-17™ are trademarks of Children's Medical Research Institute and Newcastle Innovation Ltd.

Properties

Storage instructions

Store at +4°C (desiccating conditions). Do not freeze.

Components 1 kit
ab120462 - Iminodyn-17™ 1 x 1mg
ab120461 - Iminodyn-22™ 1 x 1mg

Research areas

Biochemicals >> Research Area >> Stroke >> Signaling >> Endocytosis & exocytosis >> Dynamin
Biochemicals >> Research Area >> Respiratory disease >> Signaling >> Endocytosis & exocytosis >> Dynamin
Biochemicals >> Research Area >> Pain & inflammation >> Signaling >> Endocytosis & exocytosis >> Dynamin
Biochemicals >> Research Area >> Obesity >> Signaling >> Endocytosis & exocytosis >> Dynamin
Biochemicals >> Research Area >> Hypertension >> Signaling >> Endocytosis & exocytosis >> Dynamin
Biochemicals >> Research Area >> Heart disease >> Signaling >> Endocytosis & exocytosis >> Dynamin
Biochemicals >> Research Area >> Diabetes >> Signaling >> Endocytosis & exocytosis >> Dynamin
Biochemicals >> Research Area >> Cancer >> Signaling >> Endocytosis & exocytosis >> Dynamin
Biochemicals >> Research Area >> Alzheimer's Disease >> Signaling >> Endocytosis & exocytosis >> Dynamin
Biochemicals >> Pharmacology >> Signaling >> Endocytosis & exocytosis >> Dynamin
Biochemicals >> Pharmacology >> Enzymes >> ATPase & GTPase >> Inhibitors
Biochemicals >> Chemical Type >> Biochemicals
Biochemicals >> Product Range >> Kits

References for Dynamin Inhibitors: Iminodyn™ Series Kit (ab120475)

This product has been referenced in:

See 1 publication for this product

Publishing research using ab120475? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"