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Read our guarantee »Overview
Product name
Dynasore
Description
Cell permeable dynamin inhibitor
Biological description
Cell permeable dynamin inhibitor, that blocks endocytosis. Non-competitively inhibits dynamin1, dynamin2 and mitochondrial dynamin GTPase activity. Selective over other small GTPases.
Purity
> 99%
General notes
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 6 months.
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Properties
Chemical name
3-Hydroxynaphthalene-2-carboxylic acid (3,4-dihydroxybenzylidene)hydrazide
Molecular Weight
322.31
Chemical structure
Molecular formula
C18H14N2O4
CAS Number
304448-55-3
Solubility
Soluble in DMSO to 100 mM
PubChem identifier
0
Storage instructions
Store at -20°C (desiccating conditions).
Research areas
Biochemicals >> Pharmacology >> Enzymes >> ATPase & GTPase >> Inhibitors
Biochemicals >> Chemical Type >> Biochemicals
References for Dynasore (ab120192)
This product has been referenced in:
- Macia E et al. Dynasore, a cell-permeable inhibitor of dynamin. Dev Cell 10:839-50 (2006).Read more (PubMed: 16740485) »
- Nankoe SR & Sever S Dynasore puts a new spin on dynamin: a surprising dual role during vesicle formation. Trends Cell Biol 16:607-9 (2006).Read more (PubMed: 17064900) »
See all 2 publications for this product
Publishing research using ab120192? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"