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Anti-E2F5 antibody [220D1a] (ab59769)

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Overview

Product name

Anti-E2F5 antibody [220D1a]
See all E2F5 products (3) ...

Description

Mouse monoclonal [220D1a] to E2F5

Tested applications

WB, Dot Blotmore details

Cross reactivity

Reacts with

Human

Immunogen

Recombinant fragment (Human)

Properties

Form

Liquid

Storage instructions

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze / thaw cycles.

Storage buffer

Preservative: 0.05% Sodium Azide
Constituents: 1% BSA, PBS, pH 7.4

Concentration

Concentration information loading...

Purity

Protein G purified

Purification notes

Filtered through a 0.22 µm membrane.

Clonality

Monoclonal

Clone number

220D1a

Isotype

IgG1

Research areas

Epigenetics and Nuclear Signaling >> Transcription >> Other factors

  • Western blot - E2F5 antibody [220D1a] (ab59769)Western blot - E2F5 antibody [220D1a] (ab59769) image (enlarge)

Applications

Show applications key

Our Abpromise guarantee covers the use of ab59769 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • ShowHide1 Image

    WB

     WB: Use at an assay depe...Read more →

    WB: Use at an assay dependent dilution. Detects a band of approximately 38 kDa (predicted molecular weight: 38 kDa).

  • ShowHide

    Dot Blot

     Dot: Use at an assay dep...Read more →

    Dot: Use at an assay dependent dilution.

Target

Function

Transcriptional activator that binds to E2F sites, these sites are present in the promoter of many genes whose products are involved in cell proliferation. May mediate growth factor-initiated signal transduction. It is likely involved in the early responses of resting cells to growth factor stimulation.

Sequence similarities

Belongs to the E2F/DP family.

Cellular localization

Nucleus.

Target information above from: UniProt accessionQ15329 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).

Information by UniProt

Alternative names

  • E2F 5 antibody
  • E2F transcription factor 5 antibody
  • E2F transcription factor 5 p130 binding antibody
  • E2F-5 antibody
  • E2f5 antibody
  • E2F5_HUMAN antibody
  • p130 binding antibody
  • Transcription factor E2F5 antibody
see all

Database links

Anti-E2F5 antibody [220D1a] images:

  Western blot - E2F5 antibody [220D1a] (ab59769)

Western blot - E2F5 antibody [220D1a] (ab59769)

Anti-E2F5 antibody [220D1a] (ab59769) + immunizing peptide

Predicted band size : 38 kDa
Observed band size : 38 kDa

References for Anti-E2F5 antibody [220D1a] (ab59769)

This product has been referenced in:

  • Jiang Yet al. A potential oncogenic role of the commonly observed E2F5 overexpression in hepatocellular carcinoma. World J Gastroenterol 17:470-7 (2011). WB, IHC-P; Human.Read more (PubMed: 21274376) »
  • Wan Zet al. Human parvovirus B19 causes cell cycle arrest of human erythroid progenitors via deregulation of the E2F family of transcription factors. J Clin Invest 120:3530-44 (2010). WB; Human.Read more (PubMed: 20890043) »

See all 2 publications for this product

Publishing research using ab59769? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"