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Overview

  • Product nameEAAT1 peptideSee all EAAT1 proteins and peptides ...
  • Protein descriptionSynthetic peptide derived from within residues 1 - 100 of Human EAAT1.(Note: the amino acid sequence is proprietary)This peptide was used as an immunogen for ab41751 - EAAT1 antibody.

    • Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferInformation available upon request.
  • Concentration information loading...
  • Research Areas

    • Applications

  • Application notesThis peptide can be used with studies using ab41751.

    • Protein info

    • Alternative names
        EA6EAA1_HUMANEAAT1
        Excitatory amino acid transporter 1FLJ25094GLASTGLAST-1GLAST1Glial high affinity glutamate transporterHigh affinity neuronal glutamate transporterHigh-affinity neuronal glutamate transporterSlc1a3Sodium dependent glutamate/aspartate transporterSodium-dependent glutamate/aspartate transporterSodium-dependent glutamate/aspartate transporter 1Solute carrier family 1 (glial high affinity glutamate transporter) member 3Solute carrier family 1 member 3
      see all
  • FunctionTransports L-glutamate and also L- and D-aspartate. Essential for terminating the postsynaptic action of glutamate by rapidly removing released glutamate from the synaptic cleft. Acts as a symport by cotransporting sodium.
  • Tissue specificityHighly expressed in cerebellum, but also found in frontal cortex, hippocampus and basal ganglia.
  • Involvement in diseaseDefects in SLC1A3 are the cause of episodic ataxia type 6 (EA6) [MIM:612656]. EA6 is characterized by episodic ataxia, seizures, migraine and alternating hemiplegia.
  • Sequence similaritiesBelongs to the sodium:dicarboxylate (SDF) symporter (TC 2.A.23) family. SLC1A3 subfamily.
  • Post-translational
    modifications    Glycosylated.
  • Cellular localizationMembrane.

    • Target information above from: UniProt accession P43003 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt

    References for EAAT1 peptide (ab42682)

    ab42682 has not yet been referenced specifically in any publications.

    Publishing research using ab42682 ? Please let us know so that we can cite the reference in this datasheet

    Product Wall

    Submit an Abreview for ab42682 Submit a Question for ab42682

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    Inquiry: Dear sirs, I used the polyclonal rabbit antibody to EEAT1 (cod. ab85863) in WB. I'd like to know if the related peptide is available to prove the specificity of the antibody (one referee asked this control during the revision). In yours website t...

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    Thank you for contacting us.

    Unfortunately the blocking peptide is not available so I am sorry we are unable to with this inquiry.

    I hope this information is nevertheless helpful to you. Please do not hesitate to contact us if you need a...

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"