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Read our guarantee »Products:Neuroscience >> Neurotransmitter >> Amino Acids >> Glutamate
Anti-EAAT2 antibody [1H8] - Carboxyterminal end
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Mouse monoclonal [1H8] to EAAT2 - Carboxyterminal end
IHC-P, IHC-Frmore details
Reacts with
Human
recombinant protein corresponding to the C-terminal, cytoplasmic domain of human EAAT2.
Immunohistochemistry - Human brain, motor cortex region
Liquid
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Preservative: 15mM Sodium Azide
Constituents: Tissue culture supernatant
Tissue culture supernatant
Monoclonal
1H8
P3-NS1/1-Ag4-1
IgG2a
Neuroscience >> Neurotransmitter >> Amino Acids >> Glutamate
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - EAAT2 antibody [1H8] - Carboxyterminal end (ab49645)
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Our Abpromise guarantee covers the use of ab49645 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
IHC-P: Use at an assay dependent dilution. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
IHC-Fr: 1/20 - 1/40.
Is unsuitable for or WB.
Transports L-glutamate and also L- and D-aspartate. Essential for terminating the postsynaptic action of glutamate by rapidly removing released glutamate from the synaptic cleft. Acts as a symport by cotransporting sodium.
Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2.A.23) family. SLC1A2 subfamily.
Glycosylated.
Membrane.
Target information above from: UniProt accessionP43004
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - EAAT2 antibody [1H8] - Carboxyterminal end (ab49645)
Human brain, normal adult cerebellum: IHC-P staining for excitatory amino acid transporter 2 using ab49645. Note membrane staining of glial cells.
ab49645 has not yet been referenced specifically in any publications.
Publishing research using ab49645? Please let us know so that we can cite the reference in this datasheet
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