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Anti-EAAT2 antibody (ab69098)

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Overview

Product name

Anti-EAAT2 antibody
See all EAAT2 products (10) ...

Description

Rabbit polyclonal to EAAT2

Tested applications

WB, IHC-P, IHC-Frmore details

Cross reactivity

Reacts with

Mouse, Rat

Immunogen

A synthetic peptide as a part of rat EAAT2 conjugated to an immunogenic carrier protein

Properties

Form

Lyophilised:
Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.

Storage instructions

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C (add glycerol to a final volume of 40% for extra stability). Avoid repeated freeze / thaw cycles.

Storage buffer

Preservative: None
Constituents: Whole serum

Concentration

Concentration information loading...

Purity

Whole antiserum

Clonality

Polyclonal

Isotype

IgG

Research areas

Neuroscience >> Neurotransmitter >> Amino Acids >> Glutamate

Applications

Show applications key

Our Abpromise guarantee covers the use of ab69098 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • ShowHide

    WB

     WB: 1/300 - 1/3000.Predi...Read more →

    WB: 1/300 - 1/3000.Predicted molecular weight: 63 kDa.(This antibody has been tested in Western blot against the recombinant peptide used as an immunogen. We have no data on detection of endogenous protein.)

  • ShowHide

    IHC-P

     IHC-P: 1/300 - 1/3000.Pe...Read more →

    IHC-P: 1/300 - 1/3000.Perform heat mediated antigen retrieval before commencing with IHC staining protocol.

  • IHC-Fr

     IHC-Fr: 1/300 - 1/3000.

    IHC-Fr: 1/300 - 1/3000.

Target

Function

Transports L-glutamate and also L- and D-aspartate. Essential for terminating the postsynaptic action of glutamate by rapidly removing released glutamate from the synaptic cleft. Acts as a symport by cotransporting sodium.

Sequence similarities

Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2.A.23) family. SLC1A2 subfamily.

Post-translational
modifications

Glycosylated.

Cellular localization

Membrane.

Target information above from: UniProt accessionP43004 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).

Information by UniProt

Alternative names

  • EAA2_HUMAN antibody
  • EAAT2 antibody
  • Excitatory amino acid transporter 2 antibody
  • Excitotoxic amino acid transporter 2 antibody
  • Glial high affinity glutamate transporter antibody
  • GLT 1 antibody
  • GLT1 antibody
  • Glutamate aspartate transporter II antibody
  • Glutamate/aspartate transporter II antibody
  • Slc1a2 antibody
  • Sodium dependent glutamate aspartate transporter 2 antibody
  • Sodium-dependent glutamate/aspartate transporter 2 antibody
  • Solute carrier family 1 glial high affinity glutamate transporter member 2 antibody
  • Solute carrier family 1 member 2 antibody
see all

Database links

References for Anti-EAAT2 antibody (ab69098)

ab69098 has not yet been referenced specifically in any publications.

Publishing research using ab69098? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"