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Overview

  • Product nameEAAT3 peptide (493-505)See all EAAT3 proteins and peptides ...
  • Protein descriptionSynthetic peptide: C-DNEDSDTKKSYVN, corresponding to internal sequence amino acids 493-505 of Human EAAT3. This peptide was used as an immunogen for ab48005 - .

    • Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Concentration information loading...
  • SequenceC-DNEDSDTKKSYVN
  • Research Areas

    • Protein info

    • Alternative names
        EAA3_HUMANEAAC 1EAAC1
        EAAT 3Excitatory amino acid carrier 1Excitatory amino acid carrier1Excitatory amino acid transporter 3Excitatory amino acid transporter3Excitatory amino-acid carrier 1GLUTAMATE TRANSPORTER, HIGH-AFFINITYMEAAC 1MEAAC1Neuronal and epithelial glutamate transporterREAAC 1REAAC1Slc1 a1Slc1a 1Slc1a1Sodium dependent glutamate/aspartate transporter 3Sodium-dependent glutamate/aspartate transporter 3Solute carrier family 1 (neuronal / epithelial high affinity glutamate transporter, system Xag), member 1SOLUTE CARRIER FAMILY 1 (NEURONAL/EPITHELIAL HIGH AFFINITY GLUTAMATE TRANSPORTER), MEMBER 1Solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1Solute carrier family 1 member 1Solute carrier family 1, member 1
      see all
  • FunctionTransports L-glutamate and also L- and D-aspartate. Essential for terminating the postsynaptic action of glutamate by rapidly removing released glutamate from the synaptic cleft. Acts as a symport by cotransporting sodium. Negatively regulated by ARL6IP5.
  • Tissue specificityExpressed in all tissues tested including liver, muscle, testis, ovary, retinoblastoma cell line, neurons and brain (in which there was dense expression in substantia nigra, red nucleus, hippocampus and in cerebral cortical layers).
  • Sequence similaritiesBelongs to the sodium:dicarboxylate (SDF) symporter (TC 2.A.23) family. SLC1A1 subfamily.
  • Post-translational
    modifications    Glycosylated.
  • Cellular localizationMembrane.

    • Target information above from: UniProt accession P43005 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt

    References for EAAT3 peptide (493-505) (ab48052)

    ab48052 has not yet been referenced specifically in any publications.

    Publishing research using ab48052 ? Please let us know so that we can cite the reference in this datasheet

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