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Western blot - EBAG9 antibody [ZR001] (ab54241)
![Western blot - EBAG9 antibody [ZR001] (ab54241)](/ps/datasheet/images/ab54241-1.jpg)
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Product Name
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EBAG9 antibody [ZR001] - Carboxyterminal end
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See all EBAG9 antibodies (4)...
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Product type
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Primary antibodies
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Description
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Mouse monoclonal [ZR001] to EBAG9 - Carboxyterminal end
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Immunogen
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Recombinant fragment (Human) derived from the C-terminal region of the EBAG9.
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Reacts with
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Hu
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Predicted to react
(species key)
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Ms, Rat (Due to sequence homology)
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Tested applications
(see key)
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ELISA, IHC-P, WB
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Abreviews
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Application notes
(see key)
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Recommended dilutions ELISA: Use at a concentration of 0.1 - 1.0 µg/ml. IHC-P: Use at a concentration of 5 - 10 µg/ml. Heat Induced Epitope Retrieval (HIER) with citrate buffer is required for immunohistochemistry of paraffin-embedded tissues. WB: Use at a concentration of 1 µg/ml. Detects a band of approximately 39 kDa (predicted molecular weight: 24 kDa).
Not yet tested in other applications. Optimal dilutions/concentrations should be determined by the end user.
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Positive control
(see definition)
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Human MCF-7 cell lysate and Human 293 cell lysate (Western blotting) and Human colon cancer tissue (Immunohistochemistry).
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Cellular localization
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Golgi apparatus; Golgi apparatus membrane; single pass type III membrane protein.
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Research areas
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Cancer >> Tumor biomarkers >> Tumor antigens Cancer >> Tumor immunology >> Tumor-associated antigens Signal Transduction >> Growth Factors/Hormones >> Hormones Tags & Cell Markers >> Cell Type Markers >> Tumor Associated
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Relevance
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EBAG9 is a type III transmembrane protein that is predominantly located in the Golgi. It induces apoptosis of natural killer (NK)/T cells and plays a role in immune invasion, possibly in relation to Epstein-Bar virus infection. EBAG9 is abundantly expressed in prostate cancer cells when compared to normal epithelial cells, and immunodetection of EBAG9 expression can be a negative prognostic indicator for patients with prostate cancer.
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Database links
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The links below go to external sites and will open in a new browser window
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Raised in
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Mouse
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Clonality
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Monoclonal
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Clone number
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ZR001
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Isotype
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IgG1
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Light chain type
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kappa
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Purity
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Tissue culture supernatant
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Storage buffer
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Preservative: 0.1% Sodium Azide Constituents: Tissue culture supernatant Material safety datasheet (MSDS) for this product: Sodium Azide MSDS
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Form
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Liquid
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Concentration
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0.100 mg/ml
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Storage instructions
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Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this EBAG9 antibody [ZR001] - Carboxyterminal end is on this datasheet. But please do contact us if you would like any reassurance! |
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See below for EBAG9 antibody [ZR001] - Carboxyterminal end images, references, products related to ab54241 and other tools.
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EBAG9 antibody [ZR001] - Carboxyterminal end images:
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Search PubMed (MEDLINE) for references to EBAG9
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EBAG9 antibody [ZR001] - Carboxyterminal end - more information
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