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Overview

  • Product nameEBV Nuclear Antigen proteinSee all EBV Nuclear Antigen proteins and peptides ...
  • Protein descriptionRecombinant mosaic protein containing the EBV Nuclear Antigen regions, 1-90, 408-498 amino acids with a ~26kDa tag.
  • Expression hostE. coli

    • Properties

  • Purity> 95 % by SDS-PAGE
  • Purification notesThis protein was purified by proprietary chromatographic techniques.
  • Biological activityThis protein is immunoreactive with sera of EBV-infected individuals
  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage bufferPreservative: None
    Constituents: 50% Glycerol, 0.5% Sarkosyl, 60mM Sodium chloride, 50mM Tris HCl, 10mM Glutathione
  • Concentration information loading...
  • Research Areas

    • Applications

    Our Abpromise guarantee covers the use of ab68991 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Application Notes
    WB
    ELISA
  • Application notesELISA: Use at an assay dependent dilution.
    WB: Use at an assay dependent dilution. The molecular weight of this shorter recombinant protein is 20 kDa.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.

    • Protein info

    • Alternative names
        EBNA1EBV nuclear antigen 1Epstein Barr nuclear antigen 1
        Epstein Barr virusHHV4Human Herpesvirus 4
      see all
  • RelevanceEpstein-Barr virus (EBV) nuclear antigen 1 (EBNA1) is the one EBV antigen that is expressed in all EBV associated malignancies. It has long been thought to go undetected by the cell mediated immune system. However, recent studies show that EBNA1 can be presented to both CD4+ and CD8+ T cells, making it a potential new target for immunotherapy of EBV related cancers.
  • Cellular localizationNuclear. Free in the nucleoplasm, somewhat associated with the chromatin and hardly, if at all associated with the nuclear matrix.

    • References for EBV Nuclear Antigen protein (ab68991)

    ab68991 has not yet been referenced specifically in any publications.

    Publishing research using ab68991 ? Please let us know so that we can cite the reference in this datasheet

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"