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Products:Signal Transduction >> Signaling Pathway >> Nuclear Signaling >> NFkB Pathway
Overview
Product name
ECSIT peptide
Protein description
Synthetic peptide corresponding to 14 amino acids near the C-terminus of ECSIT (Human).
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage buffer
Preservative: 0.02% Sodium Azide
Constituents: 0.1% BSA, PBS, pH 7.2
Concentration
Concentration information loading...
Research areas
Immunology >> Innate Immunity >> TLR Signaling
Signal Transduction >> Signaling Pathway >> Nuclear Signaling >> NFkB Pathway
Applications
Show applications key
Our Abpromise guarantee covers the use of ab39757 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
WB
Blocking
Application notes
BL: Use at an assay dependent dilution.
WB: Use at an assay dependent dilution.
ECSIT peptide is used for blocking the activity of ECSIT antibody ab21288. It blocks the antibody activity completely in Western blot by incubating the peptide with equal volume of antibody for 30 min at 37°C.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Protein info
Function
Adapter protein of the Toll-like and IL-1 receptor signaling pathway that is involved in the activation of NF-kappa-B via MAP3K1. Promotes proteolytic activation of MAP3K1. Involved in the BMP signaling pathway. Required for normal embryonic development (By similarity). Required for efficient assembly of mitochondrial NADH:ubiquinone oxidoreductase.
Sequence similarities
Belongs to the ECSIT family.
Cellular localization
Cytoplasm. Nucleus. Mitochondrion.
Target information above from: UniProt accessionQ9BQ95
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
References for ECSIT peptide (ab39757)
ab39757 has not yet been referenced specifically in any publications.
Publishing research using ab39757? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"