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Read our guarantee »Products:Signal Transduction >> Signaling Pathway >> Nuclear Signaling >> NFkB Pathway
ECSIT peptide
Synthetic peptide corresponding to 14 amino acids near the C-terminus of ECSIT (Human).
Liquid
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Preservative: 0.02% Sodium Azide
Constituents: 0.1% BSA, PBS, pH 7.2
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Immunology >> Innate Immunity >> TLR Signaling
Signal Transduction >> Signaling Pathway >> Nuclear Signaling >> NFkB Pathway
Our Abpromise guarantee covers the use of ab39757 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
BL: Use at an assay dependent dilution.
WB: Use at an assay dependent dilution.
ECSIT peptide is used for blocking the activity of ECSIT antibody ab21288. It blocks the antibody activity completely in Western blot by incubating the peptide with equal volume of antibody for 30 min at 37°C.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Adapter protein of the Toll-like and IL-1 receptor signaling pathway that is involved in the activation of NF-kappa-B via MAP3K1. Promotes proteolytic activation of MAP3K1. Involved in the BMP signaling pathway. Required for normal embryonic development (By similarity). Required for efficient assembly of mitochondrial NADH:ubiquinone oxidoreductase.
Belongs to the ECSIT family.
Cytoplasm. Nucleus. Mitochondrion.
Target information above from: UniProt accessionQ9BQ95
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
ab39757 has not yet been referenced specifically in any publications.
Publishing research using ab39757? Please let us know so that we can cite the reference in this datasheet
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