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Overview

  • Product nameECSIT peptideSee all ECSIT proteins and peptides ...
  • Protein descriptionSynthetic peptide corresponding to 14 amino acids near the C-terminus of ECSIT (Human).

    • Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage bufferPreservative: 0.02% Sodium Azide
    Constituents: 0.1% BSA, PBS, pH 7.2
  • Concentration information loading...
  • Research Areas

    • Applications

    Our Abpromise guarantee covers the use of ab39757 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Application Notes
    WB
    Blocking
  • Application notesBL: Use at an assay dependent dilution.
    WB: Use at an assay dependent dilution.
    ECSIT peptide is used for blocking the activity of ECSIT antibody ab21288. It blocks the antibody activity completely in Western blot by incubating the peptide with equal volume of antibody for 30 min at 37°C.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.

    • Protein info

    • Alternative names
        EcsitECSIT homologECSIT protein
        ECSIT_HUMANEvolutionarily conserved signaling intermediate in Toll pathwayEvolutionarily conserved signaling intermediate in Toll pathway, mitochondrialEvolutionarily conserved signaling intermediate in Toll pathwaysLikely ortholog of mouse signaling intermediate in Toll pathway evolutionarily conservedProtein SITPECSignaling intermediate in Toll pathway evolutionarily conservedSITPECSITPEC protein
      see all
  • FunctionAdapter protein of the Toll-like and IL-1 receptor signaling pathway that is involved in the activation of NF-kappa-B via MAP3K1. Promotes proteolytic activation of MAP3K1. Involved in the BMP signaling pathway. Required for normal embryonic development (By similarity). Required for efficient assembly of mitochondrial NADH:ubiquinone oxidoreductase.
  • Sequence similaritiesBelongs to the ECSIT family.
  • Cellular localizationCytoplasm. Nucleus. Mitochondrion.

    • Target information above from: UniProt accession Q9BQ95 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt

    References for ECSIT peptide (ab39757)

    ab39757 has not yet been referenced specifically in any publications.

    Publishing research using ab39757 ? Please let us know so that we can cite the reference in this datasheet

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"