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Anti-EDAR antibody (ab56803)

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Overview

Product name

Anti-EDAR antibody
See all EDAR products (3) ...

Description

Mouse monoclonal to EDAR

Tested applications

WBmore details

Cross reactivity

Reacts with

Human

Immunogen

Recombinant fragment, corresponding to amino acids 64-179 of Human EDAR

Properties

Form

Liquid

Storage instructions

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Storage buffer

Preservative: None
PBS, pH 7.2

Concentration

Concentration information loading...

Purity

Protein G purified

Clonality

Monoclonal

Isotype

IgG2b

Light chain type

kappa

  • Western blot - EDAR antibody (ab56803)Western blot - EDAR antibody (ab56803) image (enlarge)

Applications

Show applications key

Our Abpromise guarantee covers the use of ab56803 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application notes

WB: Use at a concentration of 1-5 µg/ml.

This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.

Target

Relevance

EDAR (Ectodysplasin A receptor) is a receptor for EDA isoform A1, but not for EDA isoform A2. It has a single transmembrane domain, and shows similarity to 2 separate domains of the tumor necrosis factor (TNF) receptor (TNFR) family. It mediates the activation of NF-kappa-B and JNK and may promote caspase independent cell death. Defects in EDAR are a cause of hypohidrotic ectodermal dysplasia.

Cellular localization

Membrane; Single pass type I membrane protein

Alternative names

  • Anhidrotic ectodysplasin receptor 1 antibody
  • DL antibody
  • Downless (mouse) homolog antibody
  • Downless homolog antibody
  • Downless mouse homolog of antibody
  • Ectodermal dysplasia receptor antibody
  • Ectodysplasin 1 anhidrotic receptor antibody
  • Ectodysplasin A receptor antibody
  • ED 1R antibody
  • ED 3 antibody
  • ED 5 antibody
  • ED1R antibody
  • ED3 antibody
  • ED5 antibody
  • EDA 1R antibody
  • EDA 3 antibody
  • EDA A1 receptor antibody
  • EDA A1R antibody
  • EDA1R antibody
  • EDA3 antibody
  • Tumor necrosis factor receptor superfamily member EDAR antibody
see all

Database links

Anti-EDAR antibody images:

  Western blot - EDAR antibody (ab56803)

Western blot - EDAR antibody (ab56803)

Western blot against tagged recombinant protein immunogen using ab56803 EDAR antibody at 1ug/ml. Predicted band size of immunogen is 39 kDa

References for Anti-EDAR antibody (ab56803)

ab56803 has not yet been referenced specifically in any publications.

Publishing research using ab56803? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"