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Western blot - EDAR antibody (ab56803)
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Product Name
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EDAR antibody
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See all EDAR antibodies (3)...
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Product type
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Primary antibodies
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Description
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Mouse monoclonal to EDAR
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Immunogen
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Recombinant fragment, corresponding to amino acids 64-179 of Human EDAR
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Reacts with
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Hu
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Tested applications
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WB
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Abreviews
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Application notes
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Recommended dilutions
WB: Use at a concentration of 1-5 µg/ml.
This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Cellular localization
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Membrane; Single pass type I membrane protein
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Research areas
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Chromatin and Nuclear Signaling >> Nuclear Signaling Pathways >> NFkB pathway
Signal Transduction >> Growth Factors/Hormones >> TNF
Signal Transduction >> Signaling Pathway >> Nuclear Signaling >> NFkB Pathway
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Relevance
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EDAR (Ectodysplasin A receptor) is a receptor for EDA isoform A1, but not for EDA isoform A2. It has a single transmembrane domain, and shows similarity to 2 separate domains of the tumor necrosis factor (TNF) receptor (TNFR) family. It mediates the activation of NF-kappa-B and JNK and may promote caspase independent cell death. Defects in EDAR are a cause of hypohidrotic ectodermal dysplasia.
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Database links
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The links below go to external sites and will open in a new browser window |
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Raised in
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Mouse
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Clonality
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Monoclonal
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Isotype
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IgG2b
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Light chain type
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kappa
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Purity
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Protein G purified
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Storage buffer
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Preservative: None
PBS, pH 7.2
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Form
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Liquid
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Concentration
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1.000 mg/ml
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Storage instructions
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Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this EDAR antibody is on this datasheet. But please do contact us if you would like any reassurance! |
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EDAR antibody images:
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 Western blot - EDAR antibody (ab56803)
Western blot against tagged recombinant protein immunogen using ab56803 EDAR antibody at 1ug/ml. Predicted band size of immunogen is 39 kDa
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Search PubMed (MEDLINE) for references to EDAR
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EDAR antibody - more information
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Customer reviews (feedback) regarding EDAR antibody |
Customer FAQs regarding EDAR antibody |
Protocols for EDAR antibody |
Price and availability of products related to EDAR antibody |
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EDAR antibody - other tools:
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Contact Abcam with a Technical Enquiry about EDAR antibody |
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All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
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