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Western blot - EDAR antibody (ab76399)
(enlarge)
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Product Name
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EDAR antibody
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See all EDAR antibodies (3)...
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Product type
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Primary antibodies
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Description
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Rabbit polyclonal to EDAR
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Immunogen
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Synthetic peptide corresponding to a region of Human EDAR
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Reacts with
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Hu, Ms, Rat
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Tested applications
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ELISA, WB
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Abreviews
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Application notes
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Recommended dilutions
ELISA: Use at an assay dependent dilution. Titre using peptide based assay, 1:12500.
WB: Use at a concentration of 1 µg/ml. Predicted molecular weight: 49 kDa.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Positive control
(see definition)
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Placenta lysate
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Cellular localization
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Membrane; Single pass type I membrane protein
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Research areas
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Chromatin and Nuclear Signaling >> Nuclear Signaling Pathways >> NFkB pathway
Signal Transduction >> Growth Factors/Hormones >> TNF
Signal Transduction >> Signaling Pathway >> Nuclear Signaling >> NFkB Pathway
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Relevance
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EDAR (Ectodysplasin A receptor) is a receptor for EDA isoform A1, but not for EDA isoform A2. It has a single transmembrane domain, and shows similarity to 2 separate domains of the tumor necrosis factor (TNF) receptor (TNFR) family. It mediates the activation of NF-kappa-B and JNK and may promote caspase independent cell death. Defects in EDAR are a cause of hypohidrotic ectodermal dysplasia.
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Database links
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The links below go to external sites and will open in a new browser window |
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Raised in
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Rabbit
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Clonality
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Polyclonal
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Isotype
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IgG
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Purity
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Immunogen affinity purified
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Storage buffer
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Preservative: None
Constituents: 2% Sucrose, PBS
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Form
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Liquid
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Concentration
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1.000 mg/ml
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Storage instructions
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Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this EDAR antibody is on this datasheet. But please do contact us if you would like any reassurance! |
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See below for EDAR antibody images, references, products related to ab76399 and other tools.
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EDAR antibody images:
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 Western blot - EDAR antibody (ab76399)
EDAR antibody (ab76399) at 1 µg/ml (in 5% skim milk / PBS buffer) + Placenta lysate at 10 µg
Secondary
HRP conjugated anti-Rabbit IgG at 1/50000 dilution
Predicted band size : 49 kDa
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Search PubMed (MEDLINE) for references to EDAR
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EDAR antibody - more information
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Customer reviews (feedback) regarding EDAR antibody |
Customer FAQs regarding EDAR antibody |
Protocols for EDAR antibody |
Price and availability of products related to EDAR antibody |
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EDAR antibody - related products:
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EDAR antibody - other tools:
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Contact Abcam with a Technical Enquiry about EDAR antibody |
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All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
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