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Anti-EDAR antibody (ab76399)

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Overview

Product name

Anti-EDAR antibody
See all EDAR products (3) ...

Description

Rabbit polyclonal to EDAR

Tested applications

WB, ELISAmore details

Cross reactivity

Reacts with

Human

Predicted to work with

Mouse, Rat, Chicken, Cow, Dog

Immunogen

Synthetic peptide corresponding to a region of Human EDAR

Positive control

Placenta lysate

Properties

Form

Liquid

Storage instructions

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Storage buffer

Preservative: None
Constituents: 2% Sucrose, PBS

Concentration

Concentration information loading...

Purity

Immunogen affinity purified

Clonality

Polyclonal

Isotype

IgG

Research areas

Epigenetics and Nuclear Signaling >> Nuclear Signaling Pathways >> NFkB pathway
Signal Transduction >> Growth Factors/Hormones >> TNF
Signal Transduction >> Signaling Pathway >> Nuclear Signaling >> NFkB Pathway

  • Western blot - EDAR antibody (ab76399)Western blot - EDAR antibody (ab76399) image (enlarge)

Applications

Show applications key

Our Abpromise guarantee covers the use of ab76399 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application notes

ELISA: Use at an assay dependent dilution. Titre using peptide based assay, 1:12500.
WB: Use at a concentration of 1 µg/ml. Predicted molecular weight: 49 kDa.

Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.

Target

Relevance

EDAR (Ectodysplasin A receptor) is a receptor for EDA isoform A1, but not for EDA isoform A2. It has a single transmembrane domain, and shows similarity to 2 separate domains of the tumor necrosis factor (TNF) receptor (TNFR) family. It mediates the activation of NF-kappa-B and JNK and may promote caspase independent cell death. Defects in EDAR are a cause of hypohidrotic ectodermal dysplasia.

Cellular localization

Membrane; Single pass type I membrane protein

Alternative names

  • Anhidrotic ectodysplasin receptor 1 antibody
  • DL antibody
  • Downless (mouse) homolog antibody
  • Downless homolog antibody
  • Downless mouse homolog of antibody
  • Ectodermal dysplasia receptor antibody
  • Ectodysplasin 1 anhidrotic receptor antibody
  • Ectodysplasin A receptor antibody
  • ED 1R antibody
  • ED 3 antibody
  • ED 5 antibody
  • ED1R antibody
  • ED3 antibody
  • ED5 antibody
  • EDA 1R antibody
  • EDA 3 antibody
  • EDA A1 receptor antibody
  • EDA A1R antibody
  • EDA1R antibody
  • EDA3 antibody
  • Tumor necrosis factor receptor superfamily member EDAR antibody
see all

Database links

Anti-EDAR antibody images:

  Western blot - EDAR antibody (ab76399)

Western blot - EDAR antibody (ab76399)

Anti-EDAR antibody (ab76399) at 1 µg/ml (in 5% skim milk / PBS buffer) + Placenta lysate at 10 µg

Secondary
HRP conjugated anti-Rabbit IgG at 1/50000 dilution

Predicted band size : 49 kDa

References for Anti-EDAR antibody (ab76399)

ab76399 has not yet been referenced specifically in any publications.

Publishing research using ab76399? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"