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Products:Epigenetics and Nuclear Signaling >> DNA / RNA >> RNA Processing >> Other
Overview
Product name
Anti-EDC4 antibody
See all EDC4 products (3) ...
Description
Rabbit polyclonal to EDC4
Tested applications
Cross reactivity
Reacts with
Human
Immunogen
Synthetic peptide from a region between residue 1351 and 1401 of human EDC4, AAH43616.
Positive control
Whole cell lysate from Hela cells.
Properties
Form
Liquid
Storage instructions
Store at +4°C.
Storage buffer
Preservative: 0.09% Sodium Azide
Constituents: 8mM PBS, 60mM Citrate, 150mM Tris, pH 7-8
Concentration
Concentration information loading...
Purity
Immunogen affinity purified
Clonality
Polyclonal
Isotype
IgG
Research areas
Epigenetics and Nuclear Signaling >> DNA / RNA >> RNA Processing >> Other
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Immunoprecipitation - EDC4 antibody (ab72410)
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Applications
Show applications key
Our Abpromise guarantee covers the use of ab72410 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
IP: Use at 2-5 µg/mg of lysate.
Application notes
Is unsuitable for or WB.
Target
Function
In the process of mRNA degradation, seems to play a role in mRNA decapping. Component of a complex containing DCP2 and DCP1A which functions in decapping of ARE-containing mRNAs. Promotes complex formation between DCP1A and DCP2. Enhances the catalytic activity of DCP2 (in vitro).
Sequence similarities
Belongs to the WD repeat EDC4 family.
Contains 4 WD repeats.
Post-translational
modifications
Phosphorylated upon DNA damage, probably by ATM or ATR.
Cellular localization
Cytoplasm > P-body. Nucleus.
Target information above from: UniProt accessionQ6P2E9
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Alternative names
- autoantigen antibody
- Autoantigen Ge 1 antibody
- Autoantigen Ge-1 antibody
see all
Database links
- Entrez Gene: 23644 Human
- SwissProt: Q6P2E9 Human
- Unigene: 75682 Human
Anti-EDC4 antibody images:
Immunoprecipitation - EDC4 antibody (ab72410)
Immunoprecipitation/ Western Blot of EDC4. Lane 1: ab72410 at 3µg/mg whole cell lysate. Lane 2: Control IgG. Another antibody to EDC4 was used at 1µg/ml for WB. Whole cell lysate from Hela cells at 1mg for IP, 20% of IP loaded. Chemiluminescence with an exposure time of 3 seconds.
References for Anti-EDC4 antibody (ab72410)
ab72410 has not yet been referenced specifically in any publications.
Publishing research using ab72410? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"