Loading...
You have changed your country from
to
. Please be aware that this will change the currency in the purchasing process.
Products:Signal Transduction >> Signaling Pathway >> Lipid Signaling >> Other
Overview
Product name
Anti-EDG4 antibody
See all EDG4 products (2) ...
Description
Rabbit polyclonal to EDG4
Tested applications
IHC-P, ICCmore details
Cross reactivity
Reacts with
Human
Immunogen
Synthetic peptide (unfortunately, the amino acid sequence is considered to be commercially sensitive)
Epitope
C-term
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: 0.01% Sodium Azide
Constituents: PBS, pH 7.7
Concentration
Concentration information loading...
Purity
Immunogen affinity purified
Clonality
Polyclonal
Isotype
IgG
Research areas
Epigenetics and Nuclear Signaling >> Transcription >> Domain Families >> Developmental Families >> LIM
Signal Transduction >> Signaling Pathway >> G Protein Signaling >> GPCR
Signal Transduction >> Signaling Pathway >> Lipid Signaling >> Other
Applications
Show applications key
Our Abpromise guarantee covers the use of ab13028 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
IHC-P: Use at an assay dependent dilution.
ICC: Use at an assay dependent dilution.
Target
Relevance
EDG4 belongs to a family of G-protein coupled receptors whose ligands are lysophospholipids. There are eight known members of the EDG receptor family and they are implicated in mediating growth-related effects such as induction of cellular proliferation, alterations in differentiation and survival, and suppression of apoptosis. They also evoke cellular effector functions that are dependent on cytoskeletal responses such as contraction, secretion, adhesion and chemotaxis. EDG receptors are developmentally regulated and differ in tissue distribution. They couple to multiple types of G proteins to signal through ras and MAP kinase, rho, phospholipase C, and several protein tyrosine kinases. EDG4 is expressed in testes, ovarian tumor, and leukocyte containing tissues.
Cellular localization
Plasma membrane
Alternative names
- Endothelial Cell Differentiation Gene 4 antibody
- Endothelial differentiation lysophosphatidic acid G protein coupled receptor 4 antibody
- IPA2 antibody
see all
Database links
- Entrez Gene: 9170 Human
- Omim: 605110 Human
- SwissProt: Q9HBW0 Human
- Unigene: 122575 Human
References for Anti-EDG4 antibody (ab13028)
ab13028 has not yet been referenced specifically in any publications.
Publishing research using ab13028? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"