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Product Name
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EDG4 antibody
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See all EDG4 antibodies (3)...
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Product type
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Primary antibodies
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Description
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Rabbit polyclonal to EDG4
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Immunogen
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Synthetic peptide (unfortunately, the amino acid sequence is considered to be commercially sensitive)
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Reacts with
(species key)
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Hu
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Epitope
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C-term
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Tested applications
(see key)
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ICC, IHC-P
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Abreviews
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Application notes
(see key)
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Recommended dilutions
ICC: Use at an assay dependent dilution.
IHC-P: Use at an assay dependent dilution.
Not tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Cellular localization
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Plasma membrane
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Research areas
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Chromatin and Nuclear Signaling >> Transcription >> Domain Families >> Developmental Families >> LIM
Signal Transduction >> Signaling Pathway >> G Protein Signaling >> GPCR
Signal Transduction >> Signaling Pathway >> Lipid Signaling >> Other
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Relevance
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EDG4 belongs to a family of G-protein coupled receptors whose ligands are lysophospholipids. There are eight known members of the EDG receptor family and they are implicated in mediating growth-related effects such as induction of cellular proliferation, alterations in differentiation and survival, and suppression of apoptosis. They also evoke cellular effector functions that are dependent on cytoskeletal responses such as contraction, secretion, adhesion and chemotaxis. EDG receptors are developmentally regulated and differ in tissue distribution. They couple to multiple types of G proteins to signal through ras and MAP kinase, rho, phospholipase C, and several protein tyrosine kinases. EDG4 is expressed in testes, ovarian tumor, and leukocyte containing tissues.
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Database links
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The links below go to external sites and will open in a new browser window |
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Raised in
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Rabbit
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Clonality
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Polyclonal
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Isotype
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IgG
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Purity
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Immunogen affinity purified
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Storage buffer
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Preservative: 0.01% Sodium Azide
Constituents: PBS, pH 7.7 Material safety datasheet (MSDS) for this product:
Sodium Azide MSDS
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Form
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Liquid
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Concentration
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1.000 mg/ml
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Storage instructions
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Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this EDG4 antibody is on this datasheet. But please do contact us if you would like any reassurance! |
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Search PubMed (MEDLINE) for references to EDG4
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EDG4 antibody - more information
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Customer reviews (feedback) regarding EDG4 antibody |
Customer FAQs regarding EDG4 antibody |
Protocols for EDG4 antibody |
Price and availability of products related to EDG4 antibody |
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EDG4 antibody - related products:
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EDG4 antibody - other tools:
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Contact Abcam with a Technical Enquiry about EDG4 antibody |
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All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
This product is sold under license from MBL International Corporation.
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