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Products:Neuroscience >> Neurotransmission >> Receptors / Channels >> GPCR >> More GPCR
Overview
Product name
Anti-EDG7 antibody
See all EDG7 products (3) ...
Description
Rabbit polyclonal to EDG7
Tested applications
Cross reactivity
Reacts with
Human
Immunogen
Synthetic peptide, Human. (unfortunately, the amino acid sequence is considered to be commercially sensitive) (C terminal).
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage buffer
Preservative: 0.08% Sodium Azide
Constituents: PBS (sterile filtered solution)
Concentration
Concentration information loading...
Purity
IgG fraction
Clonality
Polyclonal
Isotype
IgG
Research areas
Cardiovascular >> Atherosclerosis >> Vascular Inflammation >> Leukocyte recruitment >> Other
Signal Transduction >> Signaling Pathway >> G Protein Signaling >> GPCR
Neuroscience >> Neurotransmission >> Receptors / Channels >> GPCR >> More GPCR
Applications
Show applications key
Our Abpromise guarantee covers the use of ab16456 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
WB
Application notes
WB: Use at an assay dependent dilution. Predicted molecular weight: 42.36 kDa. Due to low expression of EDG receptors, we recommend use of Pierce Femto Signal substrate for western blot development.
Not tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Target
Function
Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities. May play a role in the development of ovarian cancer. Seems to be coupled to the G(i)/G(o) and G(q) families of heteromeric G proteins.
Tissue specificity
Most abundantly expressed in prostate, testes, pancreas, and heart, with moderate levels in lung and ovary. No detectable expression in brain, placenta, liver, skeletal muscle, kidney, spleen, thymus, small intestine, colon, or peripheral blood leukocytes.
Sequence similarities
Belongs to the G-protein coupled receptor 1 family.
Cellular localization
Cell membrane.
Target information above from: UniProt accessionQ9UBY5
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Alternative names
- Calcium mobilizing lysophosphatidic acid receptor LP A3 antibody
- Calcium mobilizing lysophosphatidic acid receptor LPA 3 antibody
- Calcium mobilizing lysophosphatidic acid receptor LPA3 antibody
see all
Database links
- Entrez Gene: 23566 Human
- Omim: 605106 Human
- SwissProt: Q9UBY5 Human
- Unigene: 674915 Human
References for Anti-EDG7 antibody (ab16456)
ab16456 has not yet been referenced specifically in any publications.
Publishing research using ab16456? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"