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Products:Neuroscience >> Cell Type Marker >> Neuron marker >> Soma marker
Overview
Product name
Anti-EEA1 antibody
See all EEA1 products (9) ...
Description
Rabbit polyclonal to EEA1
Tested applications
Cross reactivity
Reacts with
Human
Predicted to work with
Mouse
Immunogen
Synthetic peptide derived from residues 307 - 356 of human EEA1.
.
Positive control
Placenta tissue lysate.
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage buffer
Preservative: None
Constituents: 2% Sucrose, PBS
Concentration
Concentration information loading...
Purity
Immunogen affinity purified
Clonality
Polyclonal
Isotype
IgG
Research areas
Neuroscience >> Neurotransmission >> Intracellular Signaling >> Regulation
Signal Transduction >> Protein Trafficking >> Organelle Proteins
Tags & Cell Markers >> Subcellular Markers >> Organelles >> Endosome
Neuroscience >> Cell Type Marker >> Neuron marker >> Soma marker
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Western blot - EEA1 antibody (ab28503)
(enlarge)
Applications
Show applications key
Our Abpromise guarantee covers the use of ab28503 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
WB: Use a concentration of 0.06 µg/mlPredicted molecular weight: 162 kDa.
Target
Function
Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate and participates in endosomal trafficking.
Sequence similarities
Contains 1 C2H2-type zinc finger.
Contains 1 FYVE-type zinc finger.
Domain
The FYVE-type zinc finger domain mediates interactions with phosphatidylinositol 3-phosphate in membranes of early endosomes and penetrates bilayers. The FYVE domain insertion into PtdIns(3)P-enriched membranes is substantially increased in acidic conditions.
Cellular localization
Cytoplasm. Early endosome membrane.
Target information above from: UniProt accessionQ15075
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Alternative names
- Early endosome antigen 1 antibody
- Early endosome antigen 1, 162kD antibody
- Early endosome associated protein antibody
see all
Database links
- Entrez Gene: 8411 Human
- Entrez Gene: 216238 Mouse
- Omim: 605070 Human
- SwissProt: Q15075 Human
- SwissProt: Q8BL66 Mouse
- Unigene: 567367 Human
- Unigene: 210035 Mouse
Anti-EEA1 antibody images:
Western blot - EEA1 antibody (ab28503)
Anti-EEA1 antibody (ab28503) at 0.06 µg/ml + Placenta tissue lysate.
Secondary
HRP conjugated anti-Rabbit IgG diluted 1/50000 - 100000
Predicted band size : 162 kDa
References for Anti-EEA1 antibody (ab28503)
ab28503 has not yet been referenced specifically in any publications.
Publishing research using ab28503? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"