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Product Name
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EED peptide
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Product type
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Proteins and Peptides
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Peptide
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Synthetic peptide derived from within residues 1 - 100 of Human EED.
This peptide was used as an immunogen for ab4469 - EED antibody.
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Application notes
(see key)
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Recommended dilutions
This peptide can be used with studies using ab4469.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Research areas
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Chromatin and Nuclear Signaling >> Chromatin Modifying Enzymes >> Methylation >> Lysine methylation
Chromatin and Nuclear Signaling >> Chromatin Remodeling >> Polycomb Silencing >> PRC3
Chromatin and Nuclear Signaling >> Chromatin Remodeling >> Polycomb Silencing >> PRC2
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Relevance
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This gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein interacts with enhancer of zeste 2, the cytoplasmic tail of integrin beta7, immunodeficiency virus type 1 (HIV1) MA protein, and histone deacetylase proteins. This protein mediates repression of gene activity through histone deacetylation, and may act as a specific regulator of integrin function. Four transcript variants encoding distinct isoforms have been identified for this gene. The four isoforms are differentialy expressed during ES cell differentiation, with four isoforms intially expressed. Only isoform 3 then remains after differentiation.
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Storage buffer
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Preservative: None
Constituents: 0.001% Tween 20, HEPES, 2mM EDTA, 150mM Sodium Chloride
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Form
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Liquid
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Concentration
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5.000 mg/ml
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Storage instructions
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Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this EED peptide is on this datasheet. But please do contact us if you would like any reassurance! |
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Search PubMed (MEDLINE) for references to EED
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EED peptide - more information
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Customer reviews (feedback) regarding EED peptide |
Customer FAQs regarding EED peptide |
Protocols for EED peptide |
Price and availability of products related to EED peptide |
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EED peptide - related products:
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Contact Abcam with a Technical Enquiry about EED peptide |
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All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
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