Anti-EFHD2/SWS1 antibody (ab119119)
Key features and details
- Rabbit polyclonal to EFHD2/SWS1
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-EFHD2/SWS1 antibody
See all EFHD2/SWS1 primary antibodies -
Description
Rabbit polyclonal to EFHD2/SWS1 -
Host species
Rabbit -
Tested applications
Suitable for: IHC-Pmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Rat -
Immunogen
Synthetic peptide corresponding to Human EFHD2/SWS1 (N terminal) conjugated to keyhole limpet haemocyanin.
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Positive control
- Human Thymus and Tonsil tissues
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.4
Preservative: 0.02% Sodium azide
Constituent: 99% PBS -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab119119 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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IHC-P |
Use a concentration of 5 µg/ml.
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Notes |
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IHC-P
Use a concentration of 5 µg/ml. |
Target
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Function
May regulate B-cell receptor (BCR)-induced immature and primary B-cell apoptosis (By similarity). Plays a role as negative regulator of the canonical NF-kappa-B-activating branch (By similarity). Controls spontaneous apoptosis through the regulation of BCL2L1 abundance. -
Tissue specificity
Found in lymphocytes; preferentially expressed in CD8+ cells. -
Sequence similarities
Contains 2 EF-hand domains. -
Cellular localization
Membrane raft. In immature B-cell line WEHI231. - Information by UniProt
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Database links
- Entrez Gene: 79180 Human
- Entrez Gene: 27984 Mouse
- Entrez Gene: 298609 Rat
- SwissProt: Q96C19 Human
- SwissProt: Q9D8Y0 Mouse
- SwissProt: Q4FZY0 Rat
- Unigene: 465374 Human
- Unigene: 395598 Mouse
see all -
Alternative names
- EF hand domain containing protein 2 antibody
- EF hand domain family, member D2 antibody
- EF-hand domain-containing protein D2 antibody
see all
Images
Datasheets and documents
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Datasheet download
References (1)
ab119119 has been referenced in 1 publication.
- Fan CC et al. EFHD2 promotes epithelial-to-mesenchymal transition and correlates with postsurgical recurrence of stage I lung adenocarcinoma. Sci Rep 7:14617 (2017). PubMed: 29097801