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The phosphorylation status of Tyrosine 1045 regulates the degradation of activated EGFR. Autophosphorylation of Tyrosine 1045 creates a docking site for the c-cbl ubiquitination ligase.
Our Abpromise guarantee covers the use of ab24928 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
ab24928 has not yet been referenced specifically in any publications.
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