Overview

  • Product nameAnti-EHHADH antibodySee all EHHADH primary antibodies ...
  • Description
    Rabbit polyclonal to EHHADH
  • Tested applicationsWB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Recombinant fragment, corresponding to amino acids 535-723 of Human EHHADH (NM_001966).

  • Positive control
    • HepG2 and 293T cell lysates; Human fetal kidney tissue

Properties

Applications

Our Abpromise guarantee covers the use of ab94948 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/200 - 1/1000. Predicted molecular weight: 79 kDa.
IHC-P 1/100 - 1/500.

Target

  • Tissue specificityLiver and kidney. Lower amounts seen in the brain.
  • PathwayLipid metabolism; fatty acid beta-oxidation.
  • Sequence similaritiesIn the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.
    In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
  • Post-translational
    modifications
    Acetylated, leading to enhanced enzyme activity. Acetylation is enhanced by up to 80% after treatment either with trichostin A (TSA) or with nicotinamide (NAM) with highest increase on Lys-346. Acetylation and enzyme activity increased by about 1.5% on addition of fatty acids.
  • Cellular localizationPeroxisome.
  • Information by UniProt
  • Database links
  • Alternative names
    • 3 hydroxyacyl CoA dehydrogenase antibody
    • 3,2 trans enoyl CoA isomerase antibody
    • 3-hydroxyacyl-CoA dehydrogenase antibody
    • ECHD antibody
    • ECHP_HUMAN antibody
    • EHHADH antibody
    • Enoyl Coenzyme A, hydratase/3 hydroxyacyl Coenzyme A dehydrogenase antibody
    • L 3 hydroxyacyl CoA dehydrogenase antibody
    • L bifunctional protein, peroxisomal antibody
    • L PBE antibody
    • LBFP antibody
    • LBP antibody
    • MGC120586 antibody
    • MS730 antibody
    • PBE antibody
    • PBFE antibody
    • Peroxisomal bifunctional enzyme antibody
    • Peroxisomal enoyl CoA hydratase antibody
    see all

Anti-EHHADH antibody images

  • All lanes : Anti-EHHADH antibody (ab94948) at 1/500 dilution

    Lane 1 : HepG2 cell lysate
    Lane 2 : 293T cell lysate


    Predicted band size : 79 kDa
  • ab94948, at 1/100 dilution, staining EHHADH in formalin-fixed, paraffin-embedded Human fetal kidney tissue by Immunohistochemistry.

References for Anti-EHHADH antibody (ab94948)

ab94948 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"