EID1 antibody (ab14454)

Product Name 

EID1 antibody

Product type 

Primary antibodies

Description 

Rabbit polyclonal to EID1

Immunogen 

Synthetic peptide: GSGSRELSLRPSRSGA conjugated to KLH, corresponding to C terminal amino acids 34-49 of Human EID1.
BLAST 'GSGSRELSLRPSRSGA' with or

Reacts with 

Hu

Predicted to react 
(species key)

Ms
(Due to sequence homology)

Tested applications 
(see key)

IP, WB

Abreviews 

Customer reviews (see key)

Read about Abreviews

Application notes 
(see key)

Recommended dilutions
IP: Use at a concentration of 10 µg/ml.
WB: Use at a concentration of 2 - 4 µg/ml. Predicted molecular weight: 22 kDa.

Not tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.

Positive control 
(see definition)

EID1 transfected Cos1 cell lysate.

Cellular localization 

Cytoplasmic and Nuclear. Note: May shuttle between nucleus and cytoplasm.

Research areas 

Cancer >> Oncoproteins/suppressors >> Tumor suppressors >> Rb family
Chromatin and Nuclear Signaling >> Chromatin Modifying Enzymes >> Acetylation >> HAT
Chromatin and Nuclear Signaling >> Transcription >> Transcription Factors
Chromatin and Nuclear Signaling >> Transcription >> Other factors
Signal Transduction >> Second Messenger >> Nucleotide Messenger >> cAMP

Cell Biology >> Apoptosis >> Intracellular >> Associated Proteins

Relevance 

EID1 ia an acetyltransferase enzyme. It acetylates histones, giving a specific tag for transcriptional activation. EID1 also acetylates non histone proteins, like NCOA3 coactivator. It Mediates cAMP gene regulation by binding specifically to phosphorylated CREB protein and as coactivator, augments the activity of phosphorylated CREB to activate transcription of cAMP responsive genes.

Database links 

Raised in 

Rabbit

Clonality 

Polyclonal

Isotype 

IgG

Purity 

Protein A purified

Storage buffer 

Preservative: 0.05% Sodium Azide
Constituents: 30% Glycerol, 0.15M Sodium chloride, 0.1M Tris glycine. pH 7.4

Material safety datasheets (MSDS) for this product:
Glycerol MSDS
Sodium Azide MSDS

Form 

Liquid

Concentration 

1.000 mg/ml

Storage instructions 

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

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