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Product Name 

EID1 antibody

 

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Product type 

Primary antibodies

Description 

Rabbit polyclonal to EID1

Immunogen 

Synthetic peptide: GSGSRELSLRPSRSGA conjugated to KLH, corresponding to C terminal amino acids 34-49 of Human EID1.
BLAST 'GSGSRELSLRPSRSGA' with BLAST the sequence with ExPASy or BLAST the sequence with NCBI

Reacts with 

Hu

Predicted to react 
(species key)

Ms
(Due to sequence homology)

Tested applications 
(see key)

IP, WB


Abreviews 

Customer reviews
(see key)


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Application notes 
(see key)

Recommended dilutions
IP: Use at a concentration of 10 µg/ml.
WB: Use at a concentration of 2 - 4 µg/ml. Predicted molecular weight: 22 kDa.

Not tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.

Positive control 
(see definition)

EID1 transfected Cos1 cell lysate.

Cellular localization 

Cytoplasmic and Nuclear. Note: May shuttle between nucleus and cytoplasm.

Research areas 

Cancer >> Oncoproteins/suppressors >> Tumor suppressors >> Rb family
Chromatin and Nuclear Signaling >> Chromatin Modifying Enzymes >> Acetylation >> HAT
Chromatin and Nuclear Signaling >> Transcription >> Transcription Factors
Chromatin and Nuclear Signaling >> Transcription >> Other factors
Signal Transduction >> Second Messenger >> Nucleotide Messenger >> cAMP

Cell Biology >> Apoptosis >> Intracellular >> Associated Proteins

Relevance 

EID1 ia an acetyltransferase enzyme. It acetylates histones, giving a specific tag for transcriptional activation. EID1 also acetylates non histone proteins, like NCOA3 coactivator. It Mediates cAMP gene regulation by binding specifically to phosphorylated CREB protein and as coactivator, augments the activity of phosphorylated CREB to activate transcription of cAMP responsive genes.

 

EID1 antibody (ab14454)

Database links 

The links below go to external sites and will open in a new browser window

Entrez Gene

    

23741    (Human)
58521    (Mouse)

Omim

    

605894    (Human)

SwissProt

    

Q9Y6B2    (Human)
Q9DCR4    (Mouse)

Raised in 

Rabbit

Clonality 

Polyclonal

Isotype 

IgG

Purity 

Protein A purified

Storage buffer 

Preservative: 0.05% Sodium Azide
Constituents: 30% Glycerol, 0.15M Sodium chloride, 0.1M Tris glycine. pH 7.4

Material safety datasheets (MSDS) for this product:
Glycerol MSDS
Sodium Azide MSDS

Form 

Liquid

Concentration 

1.000 mg/ml

Storage instructions 

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

 

At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this EID1 antibody is on this datasheet. But please do contact us if you would like any reassurance!


 

Search PubMed (MEDLINE) for references to EID1

 

EID1 antibody - more information

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