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Overview

  • Product nameEMILIN1 protein (His tag)See all EMILIN1 proteins and peptides ...
  • Protein descriptionRecombinant fragment corresponding to amino acids 676-1016 of Human EMILIN1 with 6x His tag; 362 amino acids including tag, Predicted MWt 39.1 kDa (NP_008977.1) (UniProt Q9Y6C2).
  • Uniprot accessionQ9Y6C2
  • Molecular weight39.100kDa inclusive of tags
  • Protein length341 amino acids
  • Expression hostE. coli

    • Properties

  • Purity> 95 % by SDS-PAGE
  • Mass spectrometryMALDI-TOF-TOF
  • FormLiquid
  • Storage instructionsShipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
  • Storage bufferpH: 7.40
    Constituent: 99% PBS
  • Concentration information loading...
  • Research Areas

    • Applications

    Our Abpromise guarantee covers the use of ab116414 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Application Notes
    WB WB: Use at an assay dependent dilution.
    ELISA ELISA: Use at an assay dependent dilution.
    SDS-PAGE SDS-PAGE: Use at an assay dependent dilution.
    MS MS: Use at an assay dependent dilution.

    Protein info

    • Alternative names
        Elastin microfibril interface located proteinElastin microfibril interface located protein 1Elastin microfibril interface-located protein 1
        Elastin microfibril interfacer 1EMIL1_HUMANEMILINEMILIN 1EMILIN-1Emilin1gp115
      see all
  • FunctionMay be responsible for anchoring smooth muscle cells to elastic fibers, and may be involved not only in the formation of the elastic fiber, but also in the processes that regulate vessel assembly. Has cell adhesive capacity.
  • Tissue specificityDistributed in tissues where resilience and elastic recoil are prominent. Highest levels in the adult small intestine, aorta, lung, uterus, and appendix and in the fetal spleen, kidney, lung, and heart; intermediate expression was detected in adult liver, ovary, colon, stomach, lymph node and spleen; adult heart, bladder, prostate, adrenal gland, mammary gland, placenta and kidney showed low expression whereas a series of other adult tissues, including skeletal muscle and different regions of adult brain show no expression.
  • Sequence similaritiesContains 1 C1q domain.
    Contains 1 collagen-like domain.
    Contains 1 EMI domain.
  • Cellular localizationSecreted > extracellular space > extracellular matrix. Found mainly at the interface between amorphous elastin and microfibrils.

    • Target information above from: UniProt accession Q9Y6C2 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt

    EMILIN1 protein (His tag) images

    • Western blot - EMILIN1 protein (ab116414)
      Western blot - EMILIN1 protein (ab116414)
      10% SDS-PAGE stained with Coomassie Blue (Lane 1), immunobloting with anti-6xHis (Lane 2)

    References for EMILIN1 protein (His tag) (ab116414)

    ab116414 has not yet been referenced specifically in any publications.

    Publishing research using ab116414 ? Please let us know so that we can cite the reference in this datasheet

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