You have changed your country from  to  . Please be aware that this will change the currency in the purchasing process.

Overview

  • Product nameAnti-ENY2 antibody
  • Description
    Rabbit polyclonal to ENY2
  • Tested applicationsIHC-P more details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    antigen sequence: AINQKLMETG ERERLKELLR AKLIECGWKD QLKAHCKEVI KEKGLEHVTV DDLVAEITPK GRALVPDSVK KELLQRIRT, corresponding to amino acids 15-93 of Human ENY2.

    Run BLAST with BLAST the sequence with ExPASy Run BLAST with BLAST the sequence with NCBI
  • Positive controlHuman rectum tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab121836 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Notes
IHC-P IHC-P: 1/20 - 1/50. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • FunctionComponent of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. May also participate in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery.
  • Sequence similaritiesBelongs to the ENY2 family.
  • Cellular localizationNucleus.

    • Target information above from: UniProt accession Q9NPA8 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt
  • Database links
    • Alternative names
        1810057B09Rik antibody6720481I12 antibodyDC6 antibody
        e(y)2 antibodyEnhancer of yellow 2 transcription factor homolog antibodyeny2 antibodyENY2_HUMAN antibodyEy2 antibody
      see all

    Anti-ENY2 antibody images

    • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ENY2 antibody (ab121836)
      Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ENY2 antibody (ab121836)
      ab121836 at 1/40 dilution staining ENY2 in Paraffin-embedded Human Rectum tissue by Immunohistochemistry. Note: strong positivity in glandular cells.

    References for Anti-ENY2 antibody (ab121836)

    ab121836 has not yet been referenced specifically in any publications.

    Publishing research using ab121836 ? Please let us know so that we can cite the reference in this datasheet

    Product Wall

    Submit an Abreview for ab121836 Submit a Question for ab121836

    Displaying 1 - 1 of 1 results for Abreviews and Q&A

    10
    Votes: Highest First

    We would like to try this in western blotting. Please send the testing disocunt code that Abcam offers for untested applications.

    I am very pleased to hear you would like to accept our offer and test ab121836 in western blotting. This code will give you one free primary antibody before the expiration date. To redeem this offer, please submit an Abreview for western blotting and incl...

    Read More

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"