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Products:Signal Transduction >> Cytoskeleton / ECM >> Cytoskeleton >> Microfilaments >> Actin etc >> Actin Binding Proteins
Overview
Product name
Anti-EPB41L3 antibody
See all EPB41L3 products (4) ...
Description
Goat polyclonal to EPB41L3
Tested applications
ELISA, WBmore details
Cross reactivity
Reacts with
Human
Predicted to work with
Mouse, Rat, Dog
Immunogen
Synthetic peptide: C-HKETEI TPEDGED, corresponding to C terminal amino acids 1075-1087 of Human EPB41L3
C-HKETEITP EDGED
Positive control
Human Brain lysate.
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage buffer
Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Concentration
Concentration information loading...
Purity
Immunogen affinity purified
Clonality
Polyclonal
Isotype
IgG
Research areas
Cancer >> Oncoproteins/suppressors >> Tumor suppressors >> Other
Signal Transduction >> Cytoskeleton / ECM >> Cytoskeleton >> Microfilaments >> Actin etc >> Actin Binding Proteins
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Western blot - EPB41L3 antibody (ab40831)
(enlarge)
Applications
Show applications key
Our Abpromise guarantee covers the use of ab40831 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
ELISA
- 1 Image
WB
Application notes
ELISA: 1/2000 - antibody limit dilution.
WB: Use at a concentration of 1 - 3 µg/ml. Detects a band of approximately 150 kDa (predicted molecular weight: 121 kDa).
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Target
Relevance
EPB41L3 is an actin-binding protein originally identified as a molecule whose expression is down-regulated in lung adenocarcinoma. EPB41L3 is a member of the protein 4.1 superfamily, which encompasses structural proteins that play important roles in membrane processes via interactions with actin, spectrin, and the cytoplasmic domains of integral membrane proteins. The gene for EPB41L3 is thought to function as a tumor suppressor and localizes within chromosomal region 18p11.3, which is affected by loss of heterozygosity (LOH) in various adult tumors.
Cellular localization
Cytoplasm; cytoskeleton
Alternative names
- Differentially expressed in adenocarcinoma of the lung protein 1 antibody
- 4.1B antibody
- Band 4.1 like protein 3 antibody
see all
Database links
- Entrez Gene: 23136 Human
- Entrez Gene: 13823 Mouse
- Entrez Gene: 116724 Rat
- Omim: 605331 Human
- SwissProt: Q9Y2J2 Human
- SwissProt: Q9WV92 Mouse
- Unigene: 213394 Human
Anti-EPB41L3 antibody images:
Western blot - EPB41L3 antibody (ab40831)
Anti-EPB41L3 antibody (ab40831) at 1 µg/ml + Human brain lysate at 35 µg
Predicted band size : 121 kDa
Observed band size : 150 kDa (why is the actual band size different from the predicted?)
References for Anti-EPB41L3 antibody (ab40831)
ab40831 has not yet been referenced specifically in any publications.
Publishing research using ab40831? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"