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Read our guarantee »EPC1 peptide
Synthetic peptide derived from within residues 550 - 650 of Human EPC1. (Note: the amino acid sequence is proprietary)
Liquid
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Information available upon request.
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This peptide can be used with studies using ab5514.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage.
Belongs to the enhancer of polycomb family.
Nucleus.
Target information above from: UniProt accessionQ9H2F5
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
ab24396 has not yet been referenced specifically in any publications.
Publishing research using ab24396? Please let us know so that we can cite the reference in this datasheet
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