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EPC1 peptide (ab24396)

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Overview

Product name

EPC1 peptide

Protein description

Synthetic peptide derived from within residues 550 - 650 of Human EPC1. (Note: the amino acid sequence is proprietary)

Properties

Form

Liquid

Storage instructions

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Storage buffer

Information available upon request.

Concentration

Concentration information loading...

Research areas

Epigenetics and Nuclear Signaling >> Chromatin Modifying Enzymes >> Acetylation >> HAT
Epigenetics and Nuclear Signaling >> Chromatin Modifying Enzymes >> Acetylation

Applications

Application notes

This peptide can be used with studies using ab5514.

Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.

Protein info

Function

Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage.

Sequence similarities

Belongs to the enhancer of polycomb family.

Cellular localization

Nucleus.

Target information above from: UniProt accessionQ9H2F5 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).

Information by UniProt

References for EPC1 peptide (ab24396)

ab24396 has not yet been referenced specifically in any publications.

Publishing research using ab24396? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"