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Anti-EPO antibody [Epo1] (ab20473)

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Overview

Product name

Anti-EPO antibody [Epo1]
See all EPO products (12) ...

Description

Mouse monoclonal [Epo1] to EPO

Tested applications

ELISA, WBmore details

Cross reactivity

Reacts with

Human

Immunogen

Recombinant full length protein (Human).

Properties

Form

Liquid

Storage instructions

Store at +4°C.

Storage buffer

Preservative: 0.1% Sodium Azide
Constituents: PBS, pH 7.4

Concentration

Concentration information loading...

Purity

Protein G purified

Purification notes

>95% pure. Protein G Sepharose chromatography. Purity is tested by electrophoresis.

Clonality

Monoclonal

Clone number

Epo1

Isotype

IgG1

Research areas

Cancer >> Cancer Metabolism >> Response to hypoxia
Developmental Biology >> Organogenesis >> Hematopoietic system development
Cardiovascular >> Blood >> Erythrocytes
Stem Cells >> Hematopoietic Progenitors >> Intracellular Molecules
Signal Transduction >> Growth Factors/Hormones >> Hormones
Cardiovascular >> Angiogenesis >> Growth Factors >> Other

Applications

Show applications key

Our Abpromise guarantee covers the use of ab20473 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

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    ELISA

     ELISA: Use at an assay d...Read more →

    ELISA: Use at an assay dependent dilution.

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    WB

     WB: Use at an assay depe...Read more →

    WB: Use at an assay dependent dilution. Predicted molecular weight: 21 kDa.(Dilution optimised using Chromogenic detection.)

Target

Relevance

Human erythropoietin is member of the EPO/TPO family and encodes a secreted, glycosylated cytokine hormone composed of four alpha helical bundles. The protein is found in the plasma and regulates red cell production by promoting erythroid differentiation and initiating hemoglobin synthesis. This protein also has neuroprotective activity against a variety of potential brain injuries and antiapoptotic functions in several tissue types. It is produced by kidney or liver of adult mammals and by liver of fetal or neonatal mammals.

Cellular localization

Secreted

Alternative names

  • Erythropoietin precursor antibody
  • EP antibody
  • EP antibody
  • EPO alpha antibody
  • EPO antibody
  • Epoetin antibody
  • Erythropoetin antibody
  • Erythropoietin antibody
  • Erythropoietin antibody
  • Erythropoietin precursor antibody
  • MGC138142 antibody
see all

Database links

References for Anti-EPO antibody [Epo1] (ab20473)

This product has been referenced in:

  • Shin SKet al. Application of a bridging ELISA for detection of anti-erythropoietin binding antibodies and a cell-based bioassay for neutralizing antibodies in human sera. J Pharm Biomed Anal 52:289-93 (2010). ELISA; Human.Read more (PubMed: 20133098) »

See 1 publication for this product

Publishing research using ab20473? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"