Anti-ERK1 antibody - Carboxyterminal end (ab47992)

Overview

  • Product nameAnti-ERK1 antibody - Carboxyterminal end
    See all ERK1 primary antibodies
  • Description
    Rabbit polyclonal to ERK1 - Carboxyterminal end
  • Specificityab47992 is directed against the human p44 ERK1 protein. No reactivity is observed against p42 ERK2.
  • Tested applicationsELISA, WB, IPmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Rabbit, Cow, Human
  • Immunogen

    Synthetic peptide corresponding to the Carboxy terminal end of human p44 ERK1protein

  • Positive control
    • Mouse brain, kidney and intestine whole cell lysates.

Properties

Applications

Our Abpromise guarantee covers the use of ab47992 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA
WB
IP
  • Application notesELISA: Use at a concentration of 0.5 µg/ml.
    IP: 5 ug/mg sample.
    WB: Use at a concentration of 1 µg/ml. Predicted molecular weight: 43 kDa.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionInvolved in both the initiation and regulation of meiosis, mitosis, and postmitotic functions in differentiated cells by phosphorylating a number of transcription factors such as ELK-1. Phosphorylates EIF4EBP1; required for initiation of translation. Phosphorylates microtubule-associated protein 2 (MAP2). Phosphorylates SPZ1 (By similarity). Phosphorylates heat shock factor protein 4 (HSF4).
    • Sequence similaritiesBelongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
      Contains 1 protein kinase domain.
    • DomainThe TXY motif contains the threonine and tyrosine residues whose phosphorylation activates the MAP kinases.
    • Post-translational
      modifications
      Dually phosphorylated on Thr-202 and Tyr-204, which activates the enzyme. Dephosphorylated by PTPRJ at Tyr-204.
    • Information by UniProt
    • Database links
    • Alternative names
      • ERK 1 antibody
      • ERK antibody
      • ERK-1 antibody
      • ERK1 antibody
      • ERT 2 antibody
      • ERT2 antibody
      • Extracellular Signal Regulated Kinase 1 antibody
      • Extracellular signal related kinase 1 antibody
      • Extracellular signal-regulated kinase 1 antibody
      • HGNC6877 antibody
      • HS44KDAP antibody
      • HUMKER1A antibody
      • Insulin Stimulated MAP2 Kinase antibody
      • Insulin-stimulated MAP2 kinase antibody
      • MAP kinase 1 antibody
      • MAP kinase 3 antibody
      • MAP Kinase antibody
      • MAP kinase isoform p44 antibody
      • MAPK 1 antibody
      • MAPK 3 antibody
      • MAPK antibody
      • MAPK1 antibody
      • MAPK3 antibody
      • MGC20180 antibody
      • Microtubule Associated Protein 2 Kinase antibody
      • Microtubule-associated protein 2 kinase antibody
      • Mitogen Activated Protein Kinase 3 antibody
      • Mitogen-activated protein kinase 1 antibody
      • Mitogen-activated protein kinase 3 antibody
      • MK03_HUMAN antibody
      • OTTHUMP00000174538 antibody
      • OTTHUMP00000174541 antibody
      • p44 ERK1 antibody
      • p44 MAPK antibody
      • p44-ERK1 antibody
      • p44-MAPK antibody
      • P44ERK1 antibody
      • P44MAPK antibody
      • PRKM 3 antibody
      • PRKM3 antibody
      • Protein Kinase Mitogen Activated 3 antibody
      see all

    Anti-ERK1 antibody - Carboxyterminal end images

    • All lanes : Anti-ERK1 antibody - Carboxyterminal end (ab47992) at 1 µg/ml

      Lane 1 : Left: mouse brain whole cell lysates.
      Lane 2 : Centre: mouse kidney whole cell lysates.
      Lane 3 : Right: mouse intestine whole cell lysates.


      Predicted band size : 43 kDa
      Observed band size : 43 kDa
      Additional bands at : 40 kDa. We are unsure as to the identity of these extra bands.

    References for Anti-ERK1 antibody - Carboxyterminal end (ab47992)

    ab47992 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"