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Anti-ERK1 antibody (HRP) (ab9364)

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Overview

  • Product nameAnti-ERK1 antibody (HRP)See all ERK1 primary antibodies ...
  • Description
    Rabbit polyclonal to ERK1 (HRP)
  • ConjugationHRP
  • Conjugation notesHRP
  • SpecificityReacts with p44 ERK1 but not with p42 ERK2.
  • Tested applicationsWB, IP, ELISA more details
  • Species reactivity
    Reacts with: Mouse, Rat, Rabbit, Cow, Human, Pig
  • Immunogen

    Rat ERK C-terminal peptide conjugated to KLH and BSA.

  • EpitopeThe antigen is based on the C-terminal sequence of rat p44 MAPK (C-LKELIFQETARFQPG-NH2).
  • Positive controlUse Mouse brain extract for immunoblotting and IP.

Properties

Applications

Our Abpromise guarantee covers the use of ab9364 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Notes
WB WB: 1/250.
IP IP: Use at 4 µg/mg of lysate.
ELISA ELISA: 1/500.

Target

  • FunctionInvolved in both the initiation and regulation of meiosis, mitosis, and postmitotic functions in differentiated cells by phosphorylating a number of transcription factors such as ELK-1. Phosphorylates EIF4EBP1; required for initiation of translation. Phosphorylates microtubule-associated protein 2 (MAP2). Phosphorylates SPZ1 (By similarity). Phosphorylates heat shock factor protein 4 (HSF4).
  • Sequence similaritiesBelongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
    Contains 1 protein kinase domain.
  • DomainThe TXY motif contains the threonine and tyrosine residues whose phosphorylation activates the MAP kinases.
  • Post-translational
    modifications    Dually phosphorylated on Thr-202 and Tyr-204, which activates the enzyme. Dephosphorylated by PTPRJ at Tyr-204.

    • Target information above from: UniProt accession P27361 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt
  • Database links
    see all
  • Alternative names
      ERK 1 antibodyERK antibodyERK-1 antibody
      ERK1 antibodyERT 2 antibodyERT2 antibodyExtracellular Signal Regulated Kinase 1 antibodyExtracellular signal related kinase 1 antibodyExtracellular signal-regulated kinase 1 antibodyHGNC6877 antibodyHS44KDAP antibodyHUMKER1A antibodyInsulin Stimulated MAP2 Kinase antibodyInsulin-stimulated MAP2 kinase antibodyMAP kinase 1 antibodyMAP kinase 3 antibodyMAP Kinase antibodyMAP kinase isoform p44 antibodyMAPK 1 antibodyMAPK 3 antibodyMAPK antibodyMAPK1 antibodyMAPK3 antibodyMGC20180 antibodyMicrotubule Associated Protein 2 Kinase antibodyMicrotubule-associated protein 2 kinase antibodyMitogen Activated Protein Kinase 3 antibodyMitogen-activated protein kinase 1 antibodyMitogen-activated protein kinase 3 antibodyMK03_HUMAN antibodyOTTHUMP00000174538 antibodyOTTHUMP00000174541 antibodyp44 ERK1 antibodyp44 MAPK antibodyp44-ERK1 antibodyp44-MAPK antibodyP44ERK1 antibodyP44MAPK antibodyPRKM 3 antibodyPRKM3 antibodyProtein Kinase Mitogen Activated 3 antibody
    see all

References for Anti-ERK1 antibody (HRP) (ab9364)

ab9364 has not yet been referenced specifically in any publications.

Publishing research using ab9364 ? Please let us know so that we can cite the reference in this datasheet

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10
Votes: Highest First

I am writing to find out if this antibody can be used for Immunohistochemistry. Please write back and let me know if it is!! Thank you and have a good day. T. Lewis

This antibody has not been tested in immunohistochemistry. However, it may work, we just cannot guarantee that it will.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"