Loading...
You have changed your country from
to
. Please be aware that this will change the currency in the purchasing process.
Products:Tags & Cell Markers >> Cell Type Markers >> Epi / Endo-thelial
Overview
Product name
Anti-Endothelial Cell antibody [BW-200 ]
See all Endothelial Cell products (4) ...
Description
Mouse monoclonal [BW-200 ] to Endothelial Cell
Specificity
ab15605 reacts with endothelium of the renal glomerulus but does not stain megakaryocytes. The ab15605 epitope is expressed by endothelial tumors as well as normal endothelial cells. It is expressed by endothelium of capillaries and other blood vessels, giving a staining of cellular membrane and cytoplasmic granules.
Tested applications
IHC-P, IHC-Frmore details
Cross reactivity
Reacts with
Human
Immunogen
oat-75 small-cell lung carcinoma cell line.
Positive control
Endothelial tumors and normal endothelial cells.
Properties
Form
Liquid
Storage instructions
Aliquot and store at -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: 0.02% Sodium Azide
Constituents: 1% BSA, PBS, pH 7.2
Concentration
Concentration information loading...
Purity
Protein G purified
Primary antibody notes
All blood vessels and lymphatics are lined by endothelial cells; the layer being called the endothelium. These extraordinary cells were once considered to be simple lining cells with very few functional roles, other than to keep cells within the blood from leaking out of the vessels. However, for some years research on endothelial cells has revealed that they have an amazing array of functional and adaptive qualities. Moreover, they are the key determinants of health and disease in blood vessels and play a major role in arterial disease.
Clonality
Monoclonal
Clone number
BW-200
Isotype
IgG3
Light chain type
kappa
Research areas
Tags & Cell Markers >> Cell Type Markers >> Epi / Endo-thelial
Applications
Show applications key
Our Abpromise guarantee covers the use of ab15605 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
IHC-P
IHC-Fr
Application notes
IHC-P: Use at a concentration of 1 µg/ml (1:200).
IHC-Fr: Use at a concentration of 1 µg/ml (1:200).
Not tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Target
Relevance
The endothelium is the layer of thin specialized epithelium, comprising a simple squamous layer of cells that line the interior surface of blood vessels, forming an interface between circulating blood in the lumen and the rest of the vessel wall (simple squamous epithelium). Endothelial cells line the entire circulatory system, from the heart to the smallest capillary. Endothelial cells are involved in many aspects of vascular biology, such as vasoconstriction and vasodilation, and hence the control of blood pressure; blood clotting (thrombosis & fibrinolysis); atherosclerosis; formation of new blood vessels (angiogenesis) and inflammation and swelling (oedema). Endothelial cells also control the passage of materials, and the transit of white blood cells, into and out of the bloodstream.
References for Anti-Endothelial Cell antibody [BW-200 ] (ab15605)
ab15605 has not yet been referenced specifically in any publications.
Publishing research using ab15605? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"