Endothelial Cell antibody [BW-200 ] (ab15605)

Product Name 

Endothelial Cell antibody [BW-200 ]

Product type 

Primary antibodies

Description 

Mouse monoclonal [BW-200 ] to Endothelial Cell

Immunogen 

oat-75 small-cell lung carcinoma cell line.

Reacts with 
(species key)

Hu

Specificity 

ab15605 reacts with endothelium of the renal glomerulus but does not stain megakaryocytes.

The ab15605 epitope is expressed by endothelial tumors as well as normal endothelial cells. It is expressed by endothelium of capillaries and other blood vessels, giving a staining of cellular membrane and cytoplasmic granules.

Tested applications 
(see key)

IHC-Fr, IHC-P

Abreviews 

Customer reviews (see key)

Read about Abreviews

Application notes 
(see key)

Recommended dilutions
IHC-P: Use at a concentration of 1 µg/ml (1:200).
IHC-Fr: Use at a concentration of 1 µg/ml (1:200).

Not tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.

Positive control 
(see definition)

Endothelial tumors and normal endothelial cells.

Research areas 

Tags & Cell Markers >> Cell Type Markers >> Epi / Endo-thelial

Relevance 

The endothelium is the layer of thin specialized epithelium, comprising a simple squamous layer of cells that line the interior surface of blood vessels, forming an interface between circulating blood in the lumen and the rest of the vessel wall (simple squamous epithelium). Endothelial cells line the entire circulatory system, from the heart to the smallest capillary.
Endothelial cells are involved in many aspects of vascular biology, such as vasoconstriction and vasodilation, and hence the control of blood pressure; blood clotting (thrombosis & fibrinolysis); atherosclerosis; formation of new blood vessels (angiogenesis) and inflammation and swelling (oedema). Endothelial cells also control the passage of materials, and the transit of white blood cells, into and out of the bloodstream.




All blood vessels and lymphatics are lined by endothelial cells; the layer being called the endothelium. These extraordinary cells were once considered to be simple lining cells with very few functional roles, other than to keep cells within the blood from leaking out of the vessels. However, for some years research on endothelial cells has revealed that they have an amazing array of functional and adaptive qualities. Moreover, they are the key determinants of health and disease in blood vessels and play a major role in arterial disease.

Raised in 

Mouse

Clonality 

Monoclonal

Clone number 

BW-200

Isotype 

IgG3

Light chain type 

kappa

Purity 

Protein G purified

Storage buffer 

Preservative: 0.02% Sodium Azide
Constituents: 1% BSA, PBS, pH 7.2

Material safety datasheet (MSDS) for this product:
Sodium Azide MSDS

Form 

Liquid

Concentration 

0.200 mg/ml

Storage instructions 

Aliquot and store at -80°C. Avoid repeated freeze / thaw cycles.

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