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Product Name
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Eph receptor B6 antibody
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See all Eph receptor B6 antibodies (6)...
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Product type
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Primary antibodies
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Description
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Goat polyclonal to Eph receptor B6
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Immunogen
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Purified recombinant mouse EphB6 extracellular domain.
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Reacts with
(species key)
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Ms
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Specificity
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The antibody shows no cross-reactivity with recombinant human EphA1, recombinant mouse EphA3, recombinant mouse EphA4, recombinant rat EphA5, recombinant mouse EphA6, recombinant mouse EphA7, recombinant mouse EphB1, recombinant mouse Ephrin-B2, and recombinant mouse Ephrin-B3.
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Tested applications
(see key)
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Dot, ELISA
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Abreviews
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Application notes
(see key)
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Recommended dilutions
Dot: Use at a concentration of 0.1 - 0.2 µg/ml, determined using recombinant mouse EphB6, detection limit 10ng/lane.
ELISA: Use at a concentration of 0.5 - 1 µg/ml, determined using recombinant mouse EphB6, detection limit 0.3 ng/well.
Not tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Cellular localization
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Cell Membrane; Single-pass type I membrane protein.
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Research areas
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Neuroscience >> Neurotransmission >> Receptors / Channels >> Tyrosine Kinase Receptors
Neuroscience >> Neurology process >> Growth and Development >> Axonal Guidance Proteins
Neuroscience >> Cell Type Marker >> Neuron marker >> Growth Cone
Neuroscience >> Neurotransmission >> Intracellular Signaling >> Kinases
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Relevance
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Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The ephrin receptor encoded by this gene lacks the kinase activity of most receptor tyrosine kinases and binds to ephrin-B ligands.
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Database links
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The links below go to external sites and will open in a new browser window Entrez Gene | | 13848 (Mouse)
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Raised in
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Goat
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Clonality
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Polyclonal
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Isotype
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IgG
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Purity
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Immunogen affinity purified
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Storage buffer
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Preservative: None
Constituents: PBS
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Form
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Liquid
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Concentration
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0.100 mg/ml
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Storage instructions
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Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this Eph receptor B6 antibody is on this datasheet. But please do contact us if you would like any reassurance! |
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Search PubMed (MEDLINE) for references to Eph receptor B6
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