EpiSeeker DNMT3B Inhibitor Screening Assay Kit (ab113466)
- Product nameEpiSeeker DNMT3B Inhibitor Screening Assay KitSee all DNMT3B kits ...
- Assay time3h 00m
- Species reactivityReacts with: Mouse, Human
Predicted to work with: all Mammals
- Product overview
DNMT3B (DNA (cytosine-5)-methyltransferase 3B) belongs to the DNMT family, it is required for genome de novo methylation and it is essential for establishment of DNA methylation patterns during development. The selective inhibition of DNMT3B may lead to demethylation and expression of silenced tumor suppressor genes. Thus, the selective DNMT3B inhibitors could be a new addition to cancer therapeutic agents.
EpiSeeker DNMT3B Inhibitor Screening Assay Kit (ab113466) allows the user to selectively screen DNMT3B activity/inhibitors in an ELISA-like format. The kit is ready-to-use and provides all the essential components needed to carry out a successful DNMT3B activity/inhibitor screening experiment without the need for radioactivity or any special equipment.
Not sure if this is the right product for you? Check out our EpiSeeker DNMT Product Guide for help.
Store EMH3 and EMH5 at –20°C away from light.
Store EMH1, EMH2, EMH4, EMH6 and the 8-Well Substrate-Coated Strips at 4°C away from light.
Store EMH7 at room temperature.
The kit is stable for up to 6 months from the shipment date, when stored properly.
- Tested applicationsFunctional Studies more details
- Storage instructionsPlease refer to protocols.
Components 48 tests 96 tests 8-well Substrate-Coated Strip (with frame) 6 units 12 units EMH1 (10X Wash Buffer) 1 x 11ml 1 x 22ml EMH2 (DNMT Assay Buffer) 1 x 2ml 1 x 4ml EMH3 (Adomet, 8 mM) 1 x 35µl 1 x 70µl EMH4 (Capture Antibody) 1 x 5µl 1 x 10µl EMH5 (Detection Antibody) 1 x 10µl 1 x 20µl EMH6 (Developing Solution) 1 x 6ml 1 x 12ml EMH7 (Stop Solution) 1 x 3ml 1 x 6ml
- Research Areas
Our Abpromise guarantee covers the use of ab113466 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
References for EpiSeeker DNMT3B Inhibitor Screening Assay Kit (ab113466)
ab113466 has not yet been referenced specifically in any publications.