Estradiol 17-Beta Human ELISA Kit (ab108667)
- Product nameEstradiol 17-Beta Human ELISA Kit
- Tests1 x 96 well plate
- Sample typeSerum, Plasma
- Assay typeCompetitive
- Sensitivity8.68 pg/ml
- Range20 pg/ml - 2000 pg/ml
- Species reactivityReacts with: Human
- Product overview
ab108667 Competitive immunoenzymatic colorimetric method for quantitative determination of Estradiol 17-beta in human serum or plasma.
Estradiol 17-beta is a sex hormone. It represents the major Estrogen in humans. Estradiol 17-beta has not only a critical impact on reproductive and sexual functioning, but also affects other organs including bone structure. During the reproductive years most Estradiol 17-beta in women is produced by the ovaries, smaller amounts of Estradiol 17-beta are also produced by the adrenal cortex. In men, the testes produce Estradiol 17-beta. In plasma Estradiol 17-beta is largely bound to sex hormone binding globulin (SHBG), also to albumin, only a fraction is free and biologically active. Serum Estradiol 17-beta measurement in women reflects primarily the activity of the ovaries. During pregnancy v levels, including Estradiol 17-beta, rise steadily towards term. Estradiol 17-beta increases due to placental production. In adult premenopausal women, ovarian production of Estradiol 17-beta is stimulated by luteinizing hormone (LH) and the follicle-stimulating hormone (FSH) during the menstrual cycle. In adult women, Estradiol 17-beta levels are measured in the evaluation of fertility and menstrual irregularities, and to monitor ovarian follicular function during induction of ovulation. In the female, Estradiol 17-beta acts as a growth hormone for tissue of the reproductive organs. The development of secondary sexual characteristics in women is driven by Estradiol 17-beta. Estradiol 17-beta is involved also in men fertility. Estradiol 17-beta regulates the bone maintenance. Post-menopause women experience an accelerated loss of bone mass due to a relative Estradiol 17-beta deficiency. Estradiol 17-beta affects the production of multiple proteins including lipoproteins, binding proteins, and proteins responsible for blood clotting. Estrogens have been found to have neuroprotective function. The Estradiol 17-beta, for his activities, is involved in some types of cancer such as breast cancer and cancer of the uterine lining. In addition there are several benign gynaecologic conditions that are dependent on Estrogen such as endometriosis, leiomyomata uteri, and uterine bleeding.
- Tested applicationsCompetitive ELISA more details
- Storage instructionsStore at +4°C. Please refer to protocols.
Components 1 x 96 tests Anti- Estradiol 17-beta IgG Coated Wells 1 unit Cover foils 1 unit Estradiol 17-beta -HRP conjugate 1 x 22ml Estradiol 17-beta Standard 0 1 x 1ml Estradiol 17-beta Standards 1-5 5 x 0.5ml Estradiol Control 1 x 0.5ml Stop Solution 1 x 15ml Strip holder 1 unit TMB Substrate Solution 1 x 15ml Wash solution 10 x conc 1 x 50ml
- Research Areas
Our Abpromise guarantee covers the use of ab108667 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
References for Estradiol 17-Beta Human ELISA Kit (ab108667)
ab108667 has not yet been referenced specifically in any publications.