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Overview

  • Product nameEstriol Free Human ELISA KitSee all Estriol kits ...
  • Detection methodColorimetric
  • Tests
    1 x 96 test
  • Sample type
    Serum, Plasma
  • Assay typeCompetitive
  • Sensitivity
    = 0.05 ng/ml
  • Range
    0.1 ng/ml - 12 ng/ml
  • Recovery

    101.6 %

  • Assay durationMultiple steps standard assay
  • Species reactivity
    Reacts with: Human
  • Product overview

    ab108671 Estriol Human ELISA Kit is a competitive immunoenzymatic colorimetric method for quantitative determination of free Estriol in serum or plasma.

    Estriol is one of the three main estrogens produced by the human body. It is only produced in significant amounts during pregnancy as it is made by the fetus. During pregnancy the production of estriol depends on an intact maternal-placental-fetal unit. Fetal-placental production of estriol leads to a progressive rise in maternal circulating levels reaching a late-gestational peak several orders of magnitude greater than nonpregnant levels. In the maternal circulation, estriol undergoes rapid conjugation in the liver followed by urinary excretion with a halflife of ~20 minutes. Since normal estriol production depends on an intact maternal-placental-fetal circulation and functional fetal metabolism, maternal estriol levels have been used to monitor fetal status during pregnancy, particularly during the third trimester. DHEA is produced by the adrenal cortex of the fetus, this is converted to estriol by the placenta. If levels are abnormally low in a pregnant woman, this may indicate a problem with the development in the child. Levels of estriol in non-pregnant women do not change much after menopause, and levels are not significantly different from levels in men.

  • Tested applicationsCompetitive ELISA more details
  • PlatformMicroplate

Properties

  • Alternative names
      Oestriol

Applications

Our Abpromise guarantee covers the use of ab108671 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Notes
Competitive ELISA cELISA

Protocols

References for Estriol Free Human ELISA Kit (ab108671)

ab108671 has not yet been referenced specifically in any publications.

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Dear Sirs, I am looking for antibodies and conjugated antigens to create an ELISA test for the determination of free (unconjugated) estriol. Could you recommend any of your products for this purpose.

Thank you for contacting us. We have a number of antibodies directed against estriol, ab64546, ab20278 and ab44962 are sheep, mouse and rat polyclonals respectively. These have all been tested with radioimmunoassay. Unfortunately we do not have co...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"