Estriol Free Human ELISA Kit (ab108671)
- Product nameEstriol Free Human ELISA KitSee all Estriol kits ...
- Detection methodColorimetric
- Tests1 x 96 test
- Sample typeSerum, Plasma
- Assay typeCompetitive
- Sensitivity= 0.05 ng/ml
- Range0.1 ng/ml - 12 ng/ml
- Assay durationMultiple steps standard assay
- Species reactivityReacts with: Human
- Product overview
ab108671 Estriol Human ELISA Kit is a competitive immunoenzymatic colorimetric method for quantitative determination of free Estriol in serum or plasma.
Estriol is one of the three main estrogens produced by the human body. It is only produced in significant amounts during pregnancy as it is made by the fetus. During pregnancy the production of estriol depends on an intact maternal-placental-fetal unit. Fetal-placental production of estriol leads to a progressive rise in maternal circulating levels reaching a late-gestational peak several orders of magnitude greater than nonpregnant levels. In the maternal circulation, estriol undergoes rapid conjugation in the liver followed by urinary excretion with a halflife of ~20 minutes. Since normal estriol production depends on an intact maternal-placental-fetal circulation and functional fetal metabolism, maternal estriol levels have been used to monitor fetal status during pregnancy, particularly during the third trimester. DHEA is produced by the adrenal cortex of the fetus, this is converted to estriol by the placenta. If levels are abnormally low in a pregnant woman, this may indicate a problem with the development in the child. Levels of estriol in non-pregnant women do not change much after menopause, and levels are not significantly different from levels in men.
- Tested applicationsCompetitive ELISA more details
- Storage instructionsStore at +4°C. Please refer to protocols.
Components 1 x 96 tests Anti-Estriol IgG Coated Wells 12 x 8 tests Cover foils 2 units Estriol-HRP conjugate conc 1 x 0.4ml Free Estriol Standards 4 x 1ml Incubation buffer 1 x 30ml Stop Solution 1 x 12ml Strip holder 1 unit TMB Substrate Solution 1 x 12ml
- Research Areas
Our Abpromise guarantee covers the use of ab108671 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
References for Estriol Free Human ELISA Kit (ab108671)
ab108671 has not yet been referenced specifically in any publications.