Anti-Exendin 4 antibody [20] (ab23407)
Key features and details
- Mouse monoclonal [20] to Exendin 4
- Suitable for: ELISA
- Reacts with: Recombinant fragment
- Isotype: IgG1
Overview
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Product name
Anti-Exendin 4 antibody [20]
See all Exendin 4 primary antibodies -
Description
Mouse monoclonal [20] to Exendin 4 -
Host species
Mouse -
Tested applications
Suitable for: ELISAmore details -
Species reactivity
Reacts with: Recombinant fragment -
Immunogen
Synthetic peptide corresponding to Exendin 4.
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Epitope
The epitope is located in the region of amino acids 9 to 39 of exendin 4. -
General notes
The fusion partner was SP2mIL6.The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.40
Preservative: 0.097% Sodium azide
Constituents: 0.0268% PBS, 2.9% Sodium chloride -
Concentration information loading...
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Purity
Protein A purified -
Clonality
Monoclonal -
Clone number
20 -
Isotype
IgG1 -
Light chain type
kappa -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab23407 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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ELISA | (1) |
Use at an assay dependent concentration.
The antibody binds to exendin 4 when coated on ELISA wells and reacts specifically with exendin 4 in solution giving a Ka of 1.6 x 10E8 in an inhibition ELISA. The binding between ab23407 and exendin 4 is disrupted by 4.5 M MgCl2. |
Notes |
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ELISA
Use at an assay dependent concentration. The antibody binds to exendin 4 when coated on ELISA wells and reacts specifically with exendin 4 in solution giving a Ka of 1.6 x 10E8 in an inhibition ELISA. The binding between ab23407 and exendin 4 is disrupted by 4.5 M MgCl2. |
Target
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Relevance
Exendin 4 is a 39 amino acid peptide found in venom from the Gila monster Helicoderma suspectum. It is a member of the glucagon secretin family of peptide hormones and neuropeptides. Exendin 4 is a potent agonist of the GLP1 receptor and hence a potent stimulator of insulin secretion. -
Cellular localization
Secreted -
Alternative names
- Exenatide antibody
- Exendin4 antibody
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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SDS download
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Datasheet download
References (2)
ab23407 has been referenced in 2 publications.
- Navaratna T et al. Directed Evolution Using Stabilized Bacterial Peptide Display. J Am Chem Soc 142:1882-1894 (2020). PubMed: 31880439
- Zeng Z et al. Heterologous Expression and Delivery of Biologically Active Exendin-4 by Lactobacillus paracasei L14. PLoS One 11:e0165130 (2016). PubMed: 27764251