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Product Name
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Exendin 4 antibody [20]
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See all Exendin 4 antibodies (5)...
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Product type
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Primary antibodies
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Description
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Mouse monoclonal [20] to Exendin 4
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Immunogen
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Carrier coupled exendin 4.
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Species Reactivity
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Reacts with Heloderma suspectum (Gila monster).
Not yet tested in other species.
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Specificity
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This antibody recognises exendin 4. No cross reactivity with human GLP1, GLP2 or glucagon.
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Epitope
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The epitope is located in the region of amino acids 9 to 39 of exendin 4.
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Tested applications
(see key)
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ELISA
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Abreviews
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Application notes
(see key)
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Recommended dilutions
ELISA: 1/2000. The antibody binds to exendin 4 when coated on ELISA wells and reacts specifically with exendin 4 in solution giving a Ka of 1.6 x 10E8 in an inhibition ELISA. The binding between ab23407 and exendin 4 is disrupted by 4.5 M MgCl2.
Not tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Cellular localization
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Secreted
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Research areas
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Neuroscience >> Neurotransmitter >> Neuropeptides >> Hormones
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Relevance
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Exendin 4 is a 39 amino acid peptide found in venom from the Gila monster Helicoderma suspectum. It is a member of the glucagon secretin family of peptide hormones and neuropeptides. Exendin 4 is a potent agonist of the GLP1 receptor and hence a potent stimulator of insulin secretion.
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Raised in
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Mouse
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Clonality
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Monoclonal
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Clone number
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20
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Isotype
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IgG1
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Light chain type
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kappa
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Purity
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Protein A purified
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Storage buffer
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Preservative: 15mM Sodium Azide
Constituents: 500mM Sodium chloride, 10mM PBS, pH 7.4 Material safety datasheet (MSDS) for this product:
Sodium Azide MSDS
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Form
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Liquid
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Concentration
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1.000 mg/ml
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Storage instructions
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Store at +4°C in the dark.
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Notes
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The fusion partner was SP2mIL6.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this Exendin 4 antibody [20] is on this datasheet. But please do contact us if you would like any reassurance! |
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Search PubMed (MEDLINE) for references to Exendin 4
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Exendin 4 antibody [20] - more information
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