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Anti-Exendin 4 antibody [20] (ab23407)

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Overview

Product name

Anti-Exendin 4 antibody [20]
See all Exendin 4 products (7) ...

Description

Mouse monoclonal [20] to Exendin 4

Specificity

This antibody recognises exendin 4. No cross reactivity with human GLP1, GLP2 or glucagon.

Tested applications

ELISAmore details

Cross reactivity

Reacts with Heloderma suspectum (Gila monster). Not yet tested in other species.

Immunogen

Carrier coupled exendin 4.

Epitope

The epitope is located in the region of amino acids 9 to 39 of exendin 4.

General notes

The fusion partner was SP2mIL6.

Properties

Form

Liquid

Storage instructions

Store at +4°C in the dark.

Storage buffer

Preservative: 15mM Sodium Azide
Constituents: 500mM Sodium chloride, 10mM PBS, pH 7.4

Concentration

Concentration information loading...

Purity

Protein A purified

Clonality

Monoclonal

Clone number

20

Isotype

IgG1

Light chain type

kappa

Applications

Show applications key

Our Abpromise guarantee covers the use of ab23407 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

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    ELISA

    Four stars (1 Abreview) ELISA: 1/2000(The antibo...Read more →

    ELISA: 1/2000(The antibody binds to exendin 4 when coated on ELISA wells and reacts specifically with exendin 4 in solution giving a Ka of 1.6 x 10E8 in an inhibition ELISA. The binding between ab23407 and exendin 4 is disrupted by 4.5 M MgCl2.)

Target

Relevance

Exendin 4 is a 39 amino acid peptide found in venom from the Gila monster Helicoderma suspectum. It is a member of the glucagon secretin family of peptide hormones and neuropeptides. Exendin 4 is a potent agonist of the GLP1 receptor and hence a potent stimulator of insulin secretion.

Cellular localization

Secreted

Alternative names

  • Exendin4 antibody

References for Anti-Exendin 4 antibody [20] (ab23407)

ab23407 has not yet been referenced specifically in any publications.

Publishing research using ab23407? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"