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Products:Neuroscience >> Neurotransmitter >> Neuropeptides >> Hormones
Overview
Product name
Anti-Exendin 4 antibody [24]
See all Exendin 4 products (7) ...
Description
Mouse monoclonal [24] to Exendin 4
Specificity
ab23410 recognises exendin 4. No cross reactivity with GLP 1, GLP 2 (human) or glucagon.
Tested applications
ELISAmore details
Cross reactivity
Reacts with Gila monster Helicoderma suspectum. Not yet tested in other species.
Immunogen
Carrier coupled exendin 4
Epitope
The epitope recognised by ab23410 is located in the region of amino acids 9-39 of exendin 4.
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage buffer
Preservative: 15mM Sodium Azide
Constituents: 500mM Sodium chloride, 10mM PBS, pH 7.4
Concentration
Concentration information loading...
Purity
Protein A purified
Clonality
Monoclonal
Clone number
24
Myeloma
Sp2
Isotype
IgG1
Light chain type
kappa
Research areas
Neuroscience >> Neurotransmitter >> Neuropeptides >> Hormones
Applications
Show applications key
Our Abpromise guarantee covers the use of ab23410 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
ELISA
Application notes
ELISA: 1/2000.
Note: ab23410 binds to exendin 4 when coated on ELISA wells and reacts specifically with exendin 4 in solution giving a Ka of 1.8x10E8 in an inhibition ELISA. The binding between ab23410 and exendin 4 is disrupted by 0.1 M glycine, pH 3.
Not tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Target
Relevance
Exendin 4 is a 39 amino acid peptide found in venom from the Gila monster Helicoderma suspectum. It is a member of the glucagon secretin family of peptide hormones and neuropeptides. Exendin 4 is a potent agonist of the GLP1 receptor and hence a potent stimulator of insulin secretion.
Cellular localization
Secreted
Alternative names
- Exendin4 antibody
References for Anti-Exendin 4 antibody [24] (ab23410)
ab23410 has not yet been referenced specifically in any publications.
Publishing research using ab23410? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"