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Products:Cardiovascular >> Lipids / Lipoproteins >> Fatty Acids >> Binding proteins
Overview
Product name
Anti-FABP4 antibody [5B5]
See all FABP4 products (18) ...
Description
Mouse monoclonal [5B5] to FABP4
Tested applications
ELISAmore details
Cross reactivity
Reacts with
Human
Immunogen
Full length native protein (purified) (Human).
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage buffer
Preservative: 0.1% Sodium Azide
Constituents: PBS, pH 7.4
Concentration
Concentration information loading...
Purity
Protein A purified
Purification notes
>90% pure. Protein A Sepharose chromatography. Purity was tested by electrophoresis.
Clonality
Monoclonal
Clone number
5B5
Myeloma
Sp2/0
Isotype
IgG1
Research areas
Cancer >> Cancer Metabolism >> Metabolic signaling pathway >> Metabolism of lipids and lipoproteins
Cardiovascular >> Lipids / Lipoproteins >> Fatty Acids >> Metabolism
Stem Cells >> Mesenchymal Stem Cells >> Adipogenesis
Signal Transduction >> Metabolism >> Lipid metabolism
Cardiovascular >> Lipids / Lipoproteins >> Fatty Acids >> Binding proteins
Applications
Show applications key
Our Abpromise guarantee covers the use of ab19724 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
AP: Use at an assay dependent dilution.
ELISA: Use at an assay dependent dilution.
Application notes
Is unsuitable for or WB.
Target
Function
Lipid transport protein in adipocytes. Binds both long chain fatty acids and retinoic acid. Delivers long-chain fatty acids and retinoic acid to their cognate receptors in the nucleus.
Sequence similarities
Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
Domain
Forms a beta-barrel structure that accommodates hydrophobic ligands in its interior.
Cellular localization
Cytoplasm. Nucleus. Depending on the nature of the ligand, a conformation change exposes a nuclear localization motif and the protein is transported into the nucleus. Subject to constitutive nuclear export.
Target information above from: UniProt accessionP15090
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Alternative names
- adipocyte antibody
- 3T3-L1 lipid-binding protein antibody
- 422/aP2 antibody
see all
Database links
- Entrez Gene: 2167 Human
- Omim: 600434 Human
- SwissProt: P15090 Human
- Unigene: 391561 Human
References for Anti-FABP4 antibody [5B5] (ab19724)
ab19724 has not yet been referenced specifically in any publications.
Publishing research using ab19724? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"