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Products:Cardiovascular >> Lipids / Lipoproteins >> Fatty Acids >> Binding proteins
Overview
Product name
Anti-FABP4 antibody
See all FABP4 products (18) ...
Description
Rabbit polyclonal to FABP4
Tested applications
WB, ELISA, IHC-P, IPmore details
Cross reactivity
Reacts with
Mouse, Human
Immunogen
Recombinant full length protein (Human).
Properties
Form
Liquid
Storage instructions
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: None
Constituents: 0.1M Sodium chloride, 0.05M PBS, pH 7.2
Concentration
Concentration information loading...
Purity
Immunogen affinity purified
Clonality
Polyclonal
Isotype
IgG
Research areas
Cancer >> Cancer Metabolism >> Metabolic signaling pathway >> Metabolism of lipids and lipoproteins
Cardiovascular >> Lipids / Lipoproteins >> Fatty Acids >> Metabolism
Stem Cells >> Mesenchymal Stem Cells >> Adipogenesis
Signal Transduction >> Metabolism >> Lipid metabolism
Cardiovascular >> Lipids / Lipoproteins >> Fatty Acids >> Binding proteins
Applications
Show applications key
Our Abpromise guarantee covers the use of ab13979 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
WB: Use at an assay dependent dilution. Predicted molecular weight: 15 kDa.
ELISA: Use at an assay dependent dilution.
IHC-P: 1/200
IP: Use at an assay dependent dilution.
Target
Function
Lipid transport protein in adipocytes. Binds both long chain fatty acids and retinoic acid. Delivers long-chain fatty acids and retinoic acid to their cognate receptors in the nucleus.
Sequence similarities
Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
Domain
Forms a beta-barrel structure that accommodates hydrophobic ligands in its interior.
Cellular localization
Cytoplasm. Nucleus. Depending on the nature of the ligand, a conformation change exposes a nuclear localization motif and the protein is transported into the nucleus. Subject to constitutive nuclear export.
Target information above from: UniProt accessionP15090
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Alternative names
- adipocyte antibody
- 3T3-L1 lipid-binding protein antibody
- 422/aP2 antibody
see all
Database links
- Entrez Gene: 2167 Human
- Entrez Gene: 11770 Mouse
- Omim: 600434 Human
- SwissProt: P15090 Human
- SwissProt: P04117 Mouse
- Unigene: 391561 Human
- Unigene: 582 Mouse
References for Anti-FABP4 antibody (ab13979)
This product has been referenced in:
- Holm Set al. Fatty Acid binding protein 4 is associated with carotid atherosclerosis and outcome in patients with acute ischemic stroke. PLoS One 6:e28785 (2011). IHC-P; Human.Read more (PubMed: 22174896) »
- Elmasri Het al. Fatty acid binding protein 4 is a target of VEGF and a regulator of cell proliferation in endothelial cells. FASEB J 23:3865-73 (2009).Read more (PubMed: 19625659) »
See all 2 publications for this product
Publishing research using ab13979? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"