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Products:Signal Transduction >> Metabolism >> Lipid metabolism
Overview
Product name
Anti-FABP6 antibody
See all FABP6 products (3) ...
Description
Mouse polyclonal to FABP6
Tested applications
Cross reactivity
Reacts with
Human
Immunogen
Full length protein, corresponding to amino acids 1-129 of Human FABP6
Positive control
293T cell lysate
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: None
Constituents: 1X PBS, pH 7.2
Concentration
Concentration information loading...
Purity
Protein A purified
Clonality
Polyclonal
Isotype
IgG
Research areas
Cancer >> Cancer Metabolism >> Metabolic signaling pathway >> Metabolism of lipids and lipoproteins
Cancer >> Tumor biomarkers >> Other
Signal Transduction >> Metabolism >> Lipid metabolism
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Western blot - FABP6 antibody (ab67070)
(enlarge)
Applications
Show applications key
Our Abpromise guarantee covers the use of ab67070 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
- 1 Image
WB
Application notes
WB: 1/500 - 1/1000. Detects a band of approximately 14 kDa (predicted molecular weight: 14 kDa).
Detection Antibody Pair.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Target
Function
Ileal protein which stimulates gastric acid and pepsinogen secretion. Seems to be able to bind to bile salts and bilirubins. Isoform 2 is essential for the survival of colon cancer cells to bile acid-induced apoptosis.
Tissue specificity
Isoform 2 is expressed in colorectal adenocarcinomas and their adjacent normal mucosa (at protein level). Isoform 1 is expressed in the jejunum, ileum, cecum and ascending colon intestine. Isoform 2 is expressed in the gallbladder, duodenum, jejunum, ileum, cecum, ascending, transverse and descending colon, sigmoid colon and rectum.
Sequence similarities
Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
Domain
Forms a beta-barrel structure that accommodates the hydrophobic ligand in its interior.
Cellular localization
Cytoplasm and Cytoplasm. Localized close to nucleus on the apical side of both normal and neoplastic cells.
Target information above from: UniProt accessionP51161
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Alternative names
- Fabp6 antibody
- FABP6_HUMAN antibody
- Fatty acid binding protein 6, ileal (gastrotropin) antibody
see all
Database links
- Entrez Gene: 2172 Human
- Omim: 600422 Human
- SwissProt: P51161 Human
- Unigene: 519719 Human
Anti-FABP6 antibody images:
Western blot - FABP6 antibody (ab67070)
All lanes : Anti-FABP6 antibody (ab67070) at 1/500 dilution
Lane 1 : FABP6 transfected 293T cell lysate
Lane 2 : Non transfected 293T cell lysate
Lysates/proteins at 25 µg/ml per lane.
Secondary
Goat Anti Mouse IgG (H&L) HRP Conjugate at 1/2500 dilution
Predicted band size : 14 kDa
Observed band size : 14 kDa
References for Anti-FABP6 antibody (ab67070)
ab67070 has not yet been referenced specifically in any publications.
Publishing research using ab67070? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"