Anti-FAM3C/ILEI antibody (ab56065)
Key features and details
- Rabbit polyclonal to FAM3C/ILEI
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-FAM3C/ILEI antibody
See all FAM3C/ILEI primary antibodies -
Description
Rabbit polyclonal to FAM3C/ILEI -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse -
Immunogen
Synthetic peptide corresponding to Mouse FAM3C/ILEI (N terminal).
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
Storage buffer
pH: 7.2
Preservative: 0.01% Sodium azide
Constituents: 50% Glycerol (glycerin, glycerine), PBS -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab56065 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
Use a concentration of 1 µg/ml. Predicted molecular weight: 25 kDa. for 2 hours. This antibody has been tested in Western blot against the recombinant peptide used as an immunogen. We have no data on detection of endogenous protein.
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Notes |
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WB
Use a concentration of 1 µg/ml. Predicted molecular weight: 25 kDa. for 2 hours. This antibody has been tested in Western blot against the recombinant peptide used as an immunogen. We have no data on detection of endogenous protein. |
Target
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Function
May be involved in retinal laminar formation. Promotes epithelial to mesenchymal transition. -
Tissue specificity
Present in most secretory epithelia (at protein level). -
Sequence similarities
Belongs to the FAM3 family. -
Cellular localization
Secreted. Cytoplasmic vesicle. Cytoplasmic in some cancer cells. - Information by UniProt
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Database links
- Entrez Gene: 10447 Human
- Entrez Gene: 27999 Mouse
- Omim: 608618 Human
- SwissProt: Q92520 Human
- SwissProt: Q91VU0 Mouse
- Unigene: 272375 Human
- Unigene: 434053 Human
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Alternative names
- Fam3c antibody
- FAM3C_HUMAN antibody
- Family with sequence similarity 3 member C antibody
see all
Images
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Anti-FAM3C/ILEI antibody (ab56065) at 1 µg/ml + Human liver tissue lysate - total protein at 10 µg
Secondary
Goat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilution
Predicted band size: 25 kDa
Observed band size: 30 kDa why is the actual band size different from the predicted?
Additional bands at: 46 kDa. We are unsure as to the identity of these extra bands.
Datasheets and documents
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SDS download
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Datasheet download
References (3)
ab56065 has been referenced in 3 publications.
- Pan R et al. Significant effects of Ganoderma lucidum polysaccharide on lipid metabolism in diabetes may be associated with the activation of the FAM3C-HSF1-CAM signaling pathway. Exp Ther Med 22:820 (2021). PubMed: 34131443
- Xia HG et al. Degradation of HK2 by chaperone-mediated autophagy promotes metabolic catastrophe and cell death. J Cell Biol 210:705-16 (2015). PubMed: 26323688
- Chaudhury A et al. TGF-beta-mediated phosphorylation of hnRNP E1 induces EMT via transcript-selective translational induction of Dab2 and ILEI. Nat Cell Biol : (2010). PubMed: 20154680