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Anti-FANCC antibody (ab21086)

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Overview

Product name

Anti-FANCC antibody
See all FANCC products (5) ...

Description

Rabbit polyclonal to FANCC

Tested applications

WBmore details

Cross reactivity

Reacts with

Human

Immunogen

Synthetic peptide: EKLARELLKELRTQV, corresponding to C terminal amino acids 544-558 of Human FANCC.

EKLARELLKE LRTQV

Run BLAST with BLAST the sequence with ExPASyRun BLAST with BLAST the sequence with NCBI

Positive control

HeLa nuclear cell lysate

Properties

Form

Liquid

Storage instructions

Aliquot and store at -80°C. Avoid repeated freeze / thaw cycles.

Storage buffer

Preservative: None
Constituents: PBS, pH 7.2

Concentration

Concentration information loading...

Purity

Immunogen affinity purified

Clonality

Polyclonal

Isotype

IgG

Research areas

Epigenetics and Nuclear Signaling >> DNA / RNA >> DNA Damage & Repair >> Fanconi's Anemia

Applications

Show applications key

Our Abpromise guarantee covers the use of ab21086 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Target

Relevance

FANCC is a DNA repair protein that may operate in postreplication repair or a cell cycle checkpoint function. It may be implicated in interstrand DNA cross link repair and in the maintenance of normal chromosome stability. Hsp70 requires the cooperation of FANCC to suppress PKR activity and support survival of haematopoietic cells and FANCC does not require the multimeric Fanconi anemia complex to exert this function.

Cellular localization

Nuclear (major) and cytoplasmic (minor).

Alternative names

  • bA80I15.1 antibody
  • FA 3 antibody
  • FA3 antibody
  • FAC antibody
  • FACC antibody
  • Fanconi anemia complementation group C antibody
  • Fanconi anemia complementation group C protein antibody
  • Fanconi anemia group C protein antibody
  • Fanconi pancytopenia type 3 antibody
  • FLJ14675 antibody
  • Protein FACC antibody
see all

Database links

References for Anti-FANCC antibody (ab21086)

ab21086 has not yet been referenced specifically in any publications.

Publishing research using ab21086? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"