Anti-FANCD2 antibody (ab2187)

ab2187 has been referenced in 19 publications.

1. Taniguchi T et al. Disruption of the Fanconi anemia-BRCA pathway in cisplatin-sensitive ovarian tumors. Nat Med 9:568-74 (2003). PubMed: 12692539
2. Taniguchi T et al. S-phase-specific interaction of the Fanconi anemia protein, FANCD2, with BRCA1 and RAD51. Blood 100:2414-20 (2002). PubMed: 12239151
3. Howlett NG et al. Biallelic inactivation of BRCA2 in Fanconi anemia. Science 297:606-9 (2002). PubMed: 12065746
4. Ahmad SI et al. Molecular biology of Fanconi anaemia--an old problem, a new insight. Bioessays 24:439-48 (2002). PubMed: 12001267
5. Cherubini G et al. The FANC pathway is activated by adenovirus infection and promotes viral replication-dependent recombination. Nucleic Acids Res : (2011). WB, ICC/IF; Human. PubMed: 21421559
6. Baldeyron C et al. HP1{alpha} recruitment to DNA damage by p150CAF-1 promotes homologous recombination repair. J Cell Biol 193:81-95 (2011). ICC/IF; Human. PubMed: 21464229
7. Guervilly JH et al. USP1 deubiquitinase maintains phosphorylated CHK1 by limiting its DDB1-dependent degradation. Hum Mol Genet 20:2171-81 (2011). WB, ICC/IF; Human. PubMed: 21389083
8. MacKay C et al. Identification of KIAA1018/FAN1, a DNA repair nuclease recruited to DNA damage by monoubiquitinated FANCD2. Cell 142:65-76 (2010). WB; Human. PubMed: 20603015
9. Raya A et al. Disease-corrected haematopoietic progenitors from Fanconi anaemia induced pluripotent stem cells. Nature 460:53-9 (2009). ICC/IF; Human. PubMed: 19483674
10. Naim V & Rosselli F The FANC pathway and BLM collaborate during mitosis to prevent micro-nucleation and chromosome abnormalities. Nat Cell Biol 11:761-8 (2009). ICC/IF; Human. PubMed: 19465921
11. Jacome A et al. Lentiviral-mediated genetic correction of hematopoietic and mesenchymal progenitor cells from Fanconi anemia patients. Mol Ther 17:1083-92 (2009). ICC/IF; Human. PubMed: 19277017
12. Deans AJ & West SC FANCM connects the genome instability disorders Bloom's Syndrome and Fanconi Anemia. Mol Cell 36:943-53 (2009). WB; Human. PubMed: 20064461
13. Wilson JB et al. FANCG promotes formation of a newly identified protein complex containing BRCA2, FANCD2 and XRCC3. Oncogene 27:3641-52 (2008). WB, IP. PubMed: 18212739
14. Guervilly JH et al. Loss of CHK1 function impedes DNA damage-induced FANCD2 monoubiquitination but normalizes the abnormal G2 arrest in Fanconi anemia. Hum Mol Genet 17:679-89 (2008). PubMed: 18029388
15. Briot D et al. Aberrant activation of stress-response pathways leads to TNF-alpha oversecretion in Fanconi anemia. Blood 111:1913-23 (2008). PubMed: 18055871
16. Bogliolo M et al. Histone H2AX and Fanconi anemia FANCD2 function in the same pathway to maintain chromosome stability. EMBO J 26:1340-51 (2007). ICC/IF; Human. PubMed: 17304220
17. Hirano S et al. Functional relationships of FANCC to homologous recombination, translesion synthesis, and BLM. EMBO J 24:418-27 (2005). PubMed: 15616572
18. Pichierri P & Rosselli F The DNA crosslink-induced S-phase checkpoint depends on ATR-CHK1 and ATR-NBS1-FANCD2 pathways. EMBO J 23:1178-87 (2004). PubMed: 14988723
19. Hussain S et al. Direct interaction of FANCD2 with BRCA2 in DNA damage response pathways. Hum Mol Genet 13:1241-8 (2004). PubMed: 15115758