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Product Name
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FANCM antibody
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See all FANCM antibodies (2)...
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Product type
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Primary antibodies
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Description
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Rabbit polyclonal to FANCM
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Immunogen
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Synthetic peptide derived from within residues 2000 to the C-terminus of Human FANCM.
(Peptide available as ab27787.)
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Predicted to react
(species key)
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Hu
(Due to sequence homology)
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Tested applications
(see key)
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IP
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Abreviews
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Application notes
(see key)
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Recommended dilutions
IP: Use at an assay dependent dilution (PMID 20064461).
This antibody gave a positive result in ELISA against the immunizing peptide (ab27787).
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Cellular localization
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Nuclear
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Research areas
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Chromatin and Nuclear Signaling >> DNA / RNA >> DNA Damage & Repair >> Fanconi's Anemia
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Relevance
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FANCM is an ATPase required for FANCD2 ubiquitination, a key reaction in DNA repair. It binds to ssDNA but not to dsDNA. (referenced from swissprot)
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Database links
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The links below go to external sites and will open in a new browser window |
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Raised in
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Rabbit
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Clonality
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Polyclonal
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Isotype
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IgG
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Purity
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Immunogen affinity purified
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Storage buffer
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Preservative: 0.02% Sodium Azide
Constituents: 1% BSA, PBS, pH 7.4 Material safety datasheet (MSDS) for this product:
Sodium Azide MSDS
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Form
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Liquid
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Concentration
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0.400 mg/ml
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Storage instructions
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Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this FANCM antibody is on this datasheet. But please do contact us if you would like any reassurance! |
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References for FANCM antibody (ab35620)
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This product has been used in:
Deans AJ & West SC FANCM connects the genome instability disorders Bloom's Syndrome and Fanconi Anemia. Mol Cell 36:943-53 (2009). IP; Human. PubMed: 20064461
If you publish research using ab35620 please let us know so that we can cite the reference on this datasheet.
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Search PubMed (MEDLINE) for references to FANCM
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FANCM antibody - more information
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Customer reviews (feedback) regarding FANCM antibody |
Customer FAQs regarding FANCM antibody |
Protocols for FANCM antibody |
Price and availability of products related to FANCM antibody |
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FANCM antibody - related products:
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Contact Abcam with a Technical Enquiry about FANCM antibody |
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All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
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