Overview

Description

  • NatureRecombinant
  • SourceE. coli
  • Amino Acid Sequence
    • AccessionQ96JA3-3
    • SpeciesHuman
    • Molecular weight31 kDa
    • Amino acids122 to 400
    • TagsHis-DHFR tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab127667 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • FormLyophilised
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at -20ºC.

    Constituents: 0.32% Tris HCl, 0.58% Sodium chloride

  • ReconstitutionReconstitute with 50µl water.

General info

  • Alternative names
    • FAPP-2
    • FAPP2
    • hFAPP2
    • MGC3358
    • PH domain-containing family A member 8
    • Phosphatidylinositol-four-phosphate adapter protein 2
    • Phosphoinositide binding specificmember 8
    • Phosphoinositol 4 phosphate adaptor protein 2
    • Phosphoinositol 4-phosphate adapter protein 2
    • PKHA8_HUMAN
    • Pleckstrin homology domain containing family A
    • Pleckstrin homology domain containing family A (Phosphoinositide binding specific) member 8
    • Pleckstrin homology domain-containing family A member 8
    • Plekha8
    • PLEKHA8 protein
    • Serologically defined breast cancer antigen NY-BR-86
    see all
  • FunctionInvolved in TGN-to-plasma membrane transport and in the formation of post-Golgi constitutive carriers. May play a role in ensuring the coordination of the budding and the fission reactions.
  • Tissue specificityExpressed in kidney cell lines.
  • Sequence similaritiesContains 1 PH domain.
  • DomainInteracts with PIP and ARF via plekstrin homology domain.
  • Cellular localizationCytoplasm. Localized to perinuclear structures in the trans-Golgi network.
  • Target information above from: UniProt accession Q96JA3 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt

References for FAPP2 protein (His-DHFR tag) (ab127667)

ab127667 has not yet been referenced specifically in any publications.

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