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Overview

  • Product nameFAPP2 protein (His-DHFR tag)See all FAPP2 proteins and peptides ...
  • Protein descriptionRecombinant fragment corresponding to amino acids 122-400 of Human FAPP2 with N terminal His-DHFR tag; Predicted MWt 30.9 kDa excluding tag (BC002838).
  • Uniprot accessionQ96JA3-3
  • Molecular weight30.900kDa
  • Protein length279 amino acids
  • Expression hostE. coli

    • Properties

  • Purification notesPurity is >95% by SDS-PAGE.
  • FormLyophilised:Reconstitute with 50µl water.
  • Storage instructionsShipped at 4°C. Store at -20ºC.
  • Storage bufferConstituents: 0.32% Tris HCl, 0.58% Sodium chloride
  • Concentration information loading...
  • Research Areas

    • Applications

    Our Abpromise guarantee covers the use of ab127667 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Application Notes
    SDS-PAGE SDS-PAGE: Use at an assay dependent dilution.

    Protein info

    • Alternative names
        FAPP-2FAPP2hFAPP2
        MGC3358PH domain-containing family A member 8Phosphatidylinositol-four-phosphate adapter protein 2Phosphoinositide binding specificmember 8Phosphoinositol 4 phosphate adaptor protein 2Phosphoinositol 4-phosphate adapter protein 2PKHA8_HUMANPleckstrin homology domain containing family APleckstrin homology domain containing family A (Phosphoinositide binding specific) member 8Pleckstrin homology domain-containing family A member 8Plekha8PLEKHA8 proteinSerologically defined breast cancer antigen NY-BR-86
      see all
  • FunctionInvolved in TGN-to-plasma membrane transport and in the formation of post-Golgi constitutive carriers. May play a role in ensuring the coordination of the budding and the fission reactions.
  • Tissue specificityExpressed in kidney cell lines.
  • Sequence similaritiesContains 1 PH domain.
  • DomainInteracts with PIP and ARF via plekstrin homology domain.
  • Cellular localizationCytoplasm. Localized to perinuclear structures in the trans-Golgi network.

    • Target information above from: UniProt accession Q96JA3 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt

    References for FAPP2 protein (His-DHFR tag) (ab127667)

    ab127667 has not yet been referenced specifically in any publications.

    Publishing research using ab127667 ? Please let us know so that we can cite the reference in this datasheet

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