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Products:Epigenetics and Nuclear Signaling >> DNA / RNA >> DNA Damage & Repair >> DNA Damage Response >> Other
Overview
Product name
Anti-FBP1 antibody
See all FBP1 products (4) ...
Description
Mouse polyclonal to FBP1
Tested applications
Cross reactivity
Reacts with
Human
Immunogen
Full length FBP1 protein (Human)
Positive control
Human stomach tissue lysate. FBP1 transfected 293T cell lysate.
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: None
Constituents: 1X PBS, pH 7.2
Concentration
Concentration information loading...
Purity
Protein G purified
Clonality
Polyclonal
Isotype
IgG
Applications
Show applications key
Our Abpromise guarantee covers the use of ab67247 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
WB: 1/500 - 1/1000.Detects a band of approximately 37 kDa (predicted molecular weight: 37 kDa).
Target
Pathway
Carbohydrate biosynthesis; gluconeogenesis.
Involvement in disease
Defects in FBP1 are the cause of fructose-1,6-bisphosphatase deficiency (FBPD) [MIM:229700]. FBPD is inherited as an autosomal recessive disorder mainly in the liver and causes life-threatening episodes of hypoglycemia and metabolic acidosis (lactacidemia) in newborn infants or young children.
Sequence similarities
Belongs to the FBPase class 1 family.
Target information above from: UniProt accessionP09467
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Alternative names
- 6-bisphosphatase 1 antibody
- 6-bisphosphate 1-phosphohydrolase 1 antibody
- D fructose 1 6 bisphosphate 1 phosphohydrolase 1 antibody
see all
Database links
- Entrez Gene: 2203 Human
- Omim: 611570 Human
- SwissProt: P09467 Human
- Unigene: 494496 Human
Anti-FBP1 antibody images:
Western blot - FBP1 antibody (ab67247)
Anti-FBP1 antibody (ab67247) at 1/500 dilution + human stomach tissue lysate at 25 µg/ml
Secondary
Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution
Predicted band size : 37 kDa
Observed band size : 37 kDa
Western blot - FBP1 antibody (ab67247)
All lanes : Anti-FBP1 antibody (ab67247) at 1/500 dilution
Lane 1 : FBP1 transfected 293T cell lysate
Lane 2 : Non-transfected 293T cell lysate
Lysates/proteins at 25 µg/ml per lane.
Secondary
Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution
Predicted band size : 37 kDa
Observed band size : 37 kDa
References for Anti-FBP1 antibody (ab67247)
ab67247 has not yet been referenced specifically in any publications.
Publishing research using ab67247? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"