Overview
- Product nameAnti-FCGBP antibodySee all FCGBP primary antibodies ...
- DescriptionRabbit polyclonal to FCGBP
- Tested applicationsIHC-P, ICC/IF more details
- Species reactivityReacts with: Human
- Immunogen
antigen sequence, corresponding to internal sequence amino acids 4487-4596 of Human FCGBP.
- Positive controlHuman small intestine tissue; U 251 MG cells.
Properties
- FormLiquid
- Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
- Storage bufferpH: 7.20
Preservative: 0.02% Sodium azide
Constituents: 59% PBS, 40% Glycerol -
Concentration information loading... - PurityImmunogen affinity purified
- Clonality Polyclonal
- IsotypeIgG
- Research Areas
Applications
Our Abpromise guarantee covers the use of ab121199 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Notes |
|---|---|
| IHC-P | IHC-P: 1/50 - 1/200. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
| ICC/IF | ICC/IF: Use a concentration of 1 - 4 µg/ml. Fixation/Permeabilization: PFA/Triton X-100 |
Target
- FunctionMay be involved in the maintenance of the mucosal structure as a gel-like component of the mucosa.
- Tissue specificityMainly expressed in placenta and colon epithelium. Expressed in thyroid, and down-regulated in thyroid carcinomas. Present in serum, with higher levels in patients with various autoimmune diseases (at protein level).
- Sequence similaritiesContains 12 TIL (trypsin inhibitory-like) domains.
Contains 13 VWFD domains. - DomainThe N-terminal IgGFc-binding region is primate-specific.
- Cellular localizationSecreted.
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Database links
- Entrez Gene: 8857 Human
- SwissProt: Q9Y6R7 Human
- Unigene: 111732 Human
Target information above from: UniProt accession
Q9Y6R7
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010)
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Alternative names
- Fc fragment of IgG binding protein antibodyFC(GAMMA)BP antibodyFcgamma-binding protein antigen antibody
- FcgammaBP antibodyFCGBP antibodyFCGBP_HUMAN antibodyHuman Fc gamma BP antibodyIgGFc-binding protein antibody
see all
Anti-FCGBP antibody images
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-FCGBP antibody (ab121199)ab121199 at 1/100 dilution staining FCGBP in Paraffin-embedded Human Small intestine tissue by Immunohistochemistry. -
ab121199 at 4 µg/ml staining FCGBP in PFA/Triton X-100 fixed/permeabilized U 251 MG cells by Immunofluorescence (green).
References for Anti-FCGBP antibody (ab121199)
ab121199 has not yet been referenced specifically in any publications.
