Anti-FCGRT/FCRN antibody [CL3640] (ab223381)
Key features and details
- Mouse monoclonal [CL3640] to FCGRT/FCRN
- Suitable for: IHC-P, WB
- Reacts with: Human
- Isotype: IgG1
Overview
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Product name
Anti-FCGRT/FCRN antibody [CL3640]
See all FCGRT/FCRN primary antibodies -
Description
Mouse monoclonal [CL3640] to FCGRT/FCRN -
Host species
Mouse -
Tested applications
Suitable for: IHC-P, WBmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Cynomolgus monkey -
Immunogen
Recombinant fragment corresponding to Human FCGRT/FCRN aa 150-300.
Database link: P55899 -
Epitope
Binds to an epitope located within the peptide sequence GQGDFGPNSD as determined by overlapping synthetic peptides. -
Positive control
- WB: THP-1 (human monocytic leukemia cell line) cell lysate. IHC-P: Human lymph node, liver, placenta and colon tissue.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.20
Preservative: 0.02% Sodium azide
Constituents: 40% Glycerol (glycerin, glycerine), PBS -
Concentration information loading...
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Purity
Protein A purified -
Clonality
Monoclonal -
Clone number
CL3640 -
Isotype
IgG1 -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab223381 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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IHC-P |
1/5000 - 1/10000. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
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WB |
1/500 - 1/1000.
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Notes |
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IHC-P
1/5000 - 1/10000. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
WB
1/500 - 1/1000. |
Target
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Function
Binds to the Fc region of monomeric immunoglobulins gamma. Mediates the uptake of IgG from milk. Possible role in transfer of immunoglobulin G from mother to fetus. -
Sequence similarities
Belongs to the immunoglobulin superfamily. -
Cellular localization
Cell membrane. - Information by UniProt
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Database links
- Entrez Gene: 2217 Human
- Omim: 601437 Human
- SwissProt: Q8SPV9 Cynomolgus monkey
- SwissProt: P55899 Human
- Unigene: 111903 Human
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Alternative names
- Alpha chain antibody
- Fc fragment of IgG, receptor transporter, alpha antibody
- FCGRN_HUMAN antibody
see all
Images
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Anti-FCGRT/FCRN antibody [CL3640] (ab223381) at 1/500 dilution + THP-1 (human monocytic leukemia cell line) whole cell lysate
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Paraffin embedded human lymph node tissue stained for FCGRT/FCRN with ab223381 at a 1/5000 dilution in Immunohistochemical analysis.
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Paraffin embedded human colon tissue stained for FCGRT/FCRN with ab223381 at a 1/5000 dilution in Immunohistochemical analysis.
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Paraffin embedded human placenta tissue stained for FCGRT/FCRN with ab223381 at a 1/5000 dilution in Immunohistochemical analysis.
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Paraffin embedded human liver tissue stained for FCGRT/FCRN with ab223381 at a 1/5000 dilution in Immunohistochemical analysis.
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab223381 has not yet been referenced specifically in any publications.